1-Phenazinecarboxylic acid 5-oxide

Base Information

• Chemical Name: 1-Phenazinecarboxylic acid 5-oxide
• CAS No.: 27210-90-8
• Molecular Formula: C13H8N2O3
• Molecular Weight: 240.21
• Mol file: 27210-90-8.mol

Synonyms:1-Phenazinecarboxylic acid 5-oxide

Chemical Property of 1-Phenazinecarboxylic acid 5-oxide

Chemical Property:

• PSA: 75.65000
• LogP: 2.51470

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Phenazinecarboxylic acid 5-oxide

There total 10 articles about 1-Phenazinecarboxylic acid 5-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

tubermycin B (2538-68-3,102646-59-3) → 1-carboxyphenazine 5-oxide (27210-90-8)

Guidance literature:

With dihydrogen peroxide; acetic acid; In water; at 55 ℃; for 17h; Inert atmosphere;

DOI:10.1039/c3ob42416b

Reference yield:

2-bromo-3-nitro-benzoic acid (573-54-6) → 1-carboxyphenazine 5-oxide (27210-90-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 79 percent / CuCl, Cu, N-ethylmorpholine / various solvent(s) / 15 h / 70 - 80 °C

2: NaBH₄, NaOMe / methanol / Heating

3: 38 percent / 30percent H₂O₂ / acetic acid / 24 h / 55 - 60 °C

With N-ethylmorpholine;; sodium tetrahydroborate; dihydrogen peroxide; sodium methylate; copper; copper(l) chloride; In methanol; acetic acid;

DOI:10.1021/jm00388a017

Reference yield:

6-nitrodiphenylamine-2-carboxylic acid (54420-95-0) → 1-carboxyphenazine 5-oxide (27210-90-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / NaBH₄, NaOEt / ethanol / 1 h / Heating

2: 38 percent / 30percent H₂O₂ / acetic acid / 24 h / 55 - 60 °C

With sodium tetrahydroborate; dihydrogen peroxide; sodium ethanolate; In ethanol; acetic acid;

DOI:10.1021/jm00388a017

upstream raw materials:

tubermycin B

2-bromo-3-nitro-benzoic acid

6-nitrodiphenylamine-2-carboxylic acid

2-methoxy-phenylamine