BUTTPARK 121\16-95

Base Information

• Chemical Name: BUTTPARK 121\16-95
• CAS No.: 874842-90-7
• Molecular Formula: C₁₀H₂₀N₄O₃
• Molecular Weight: 244.294
• Mol file: 874842-90-7.mol

Synonyms:BUTTPARK 121\16-95;tert-Butyl 4-(hydrazinocarbonyl)-piperazine-1-carboxylate

Chemical Property of BUTTPARK 121\16-95

Chemical Property:

• PSA: 87.90000
• LogP: 1.08940

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl 4-(hydrazinocarbonyl)-piperazine-1-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BUTTPARK 121\16-95

There total 2 articles about BUTTPARK 121\16-95 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

1-tert-butyl 4-trichloromethyl piperazine-1,4-dicarboxylate (1480602-15-0) → tert-butyl 4-(hydrazinecarbonyl)piperazine-1-carboxylate (874842-90-7)

Guidance literature:

With hydrazine hydrate; In tetrahydrofuran; at 20 ℃; for 2.5h;

Reference yield:

1-t-Butoxycarbonylpiperazine (57260-71-6) → tert-butyl 4-(hydrazinecarbonyl)piperazine-1-carboxylate (874842-90-7)

Guidance literature:

Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / dichloromethane / 3.67 h / 0 - 20 °C

2: hydrazine hydrate / tetrahydrofuran / 2.5 h / 20 °C

With hydrazine hydrate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane;

upstream raw materials:

1-t-Butoxycarbonylpiperazine

1-tert-butyl 4-trichloromethyl piperazine-1,4-dicarboxylate

Refernces

• 1、 -. "1,3,4-OXADIAZOLE AND 1,3,4-THIADIAZOLE BETA-LACTAMASE INHIBITORS". . . Retrieved 2013/10/21.