(4R)-3-[(2R,3S)-3-Hydroxy-1-oxo-2-(2-propen-1-yl)-4-penten-1-yl]-4-(phenylMethyl)-2-oxazolidinone

Base Information

• Chemical Name: (4R)-3-[(2R,3S)-3-Hydroxy-1-oxo-2-(2-propen-1-yl)-4-penten-1-yl]-4-(phenylMethyl)-2-oxazolidinone
• CAS No.: 1005006-69-8
• Molecular Formula: C₁₈H₂₁NO₄
• Molecular Weight: 315.369
• Mol file: 1005006-69-8.mol

Synonyms:(4R)-3-[(2R,3S)-3-Hydroxy-1-oxo-2-(2-propen-1-yl)-4-penten-1-yl]-4-(phenylMethyl)-2-oxazolidinone

Chemical Property of (4R)-3-[(2R,3S)-3-Hydroxy-1-oxo-2-(2-propen-1-yl)-4-penten-1-yl]-4-(phenylMethyl)-2-oxazolidinone

Chemical Property:

• PSA: 66.84000
• LogP: 2.25360
• Solubility.: Dichloromethane, Ethyl Acetate, Methanol

Purity/Quality:

(4R)-3-[(2R,3S)-3-Hydroxy-1-oxo-2-(2-propen-1-yl)-4-penten-1-yl]-4-(phenylmethyl)-2-oxazolidinone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (4R)-3-[(2R,3S)-3-Hydroxy-1-oxo-2-(2-propen-1-yl)-4-penten-1-yl]-4-(phenylmethyl)-2-oxazolidinone (cas# 1005006-69-8) is a compound useful in organic synthesis.

Technology Process of (4R)-3-[(2R,3S)-3-Hydroxy-1-oxo-2-(2-propen-1-yl)-4-penten-1-yl]-4-(phenylMethyl)-2-oxazolidinone

There total 1 articles about (4R)-3-[(2R,3S)-3-Hydroxy-1-oxo-2-(2-propen-1-yl)-4-penten-1-yl]-4-(phenylMethyl)-2-oxazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C23H34BNO3 + acrolein (107-02-8,25068-14-8) → [3(2R,3S),4R]-3-(2-allyl-3-hydroxypent-4-enoyl)-4-benzyloxazolidin-2-one (1005006-69-8)

Guidance literature:

In dichloromethane; at -78 - 20 ℃;

DOI:10.1016/j.tet.2007.10.054

Reference yield: 59.0%

[3(2R,3S),4R]-3-(2-allyl-3-hydroxypent-4-enoyl)-4-benzyloxazolidin-2-one (1005006-69-8) → [3(1R,2S),4R]-4-benzyl-3-(2-hydroxycylopent-3-enecarbonyl)oxazolidin-2-one (1005006-70-1)

Guidance literature:

Grubbs catalyst first generation; In dichloromethane;

DOI:10.1016/j.tet.2007.10.054

upstream raw materials:

acrolein

Downstream raw materials:

[3(1R,2S),4R]-4-benzyl-3-(2-hydroxycylopent-3-enecarbonyl)oxazolidin-2-one

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