N-(4-CARBETHOXYPHENYL)-N-4-(6'-BENZOTHIAZOLE)AMINE

Base Information

• Chemical Name: N-(4-CARBETHOXYPHENYL)-N-4-(6'-BENZOTHIAZOLE)AMINE
• CAS No.: 458550-54-4
• Molecular Formula: C₁₆H₁₄N₂O₂S
• Molecular Weight: 298.365
• Mol file: 458550-54-4.mol

Synonyms:Benzoic acid, 4-(6-benzothiazolylamino)-, ethyl ester

Chemical Property of N-(4-CARBETHOXYPHENYL)-N-4-(6'-BENZOTHIAZOLE)AMINE

Chemical Property:

• Vapor Pressure: 2.39E-09mmHg at 25°C
• Boiling Point: 479.3°C at 760 mmHg
• Flash Point: 243.7°C
• PSA: 79.46000
• Density: 1.316g/cm³
• LogP: 4.28960

Purity/Quality:

98%min ^*data from raw suppliers

Ethyl4-(benzo[d]thiazol-6-ylamino)benzoate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(4-CARBETHOXYPHENYL)-N-4-(6'-BENZOTHIAZOLE)AMINE

There total 1 articles about N-(4-CARBETHOXYPHENYL)-N-4-(6'-BENZOTHIAZOLE)AMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

4-iodobenzoic acid ethyl ester (51934-41-9) + 6-nitrobenzo[d]thiazole (2942-06-5) → ethyl 4-(1,3-benzothiazol-6-ylamino)benzoate (458550-54-4)

Guidance literature:

4-iodobenzoic acid ethyl ester; With isopropylmagnesium chloride; In tetrahydrofuran; at -20 ℃; for 0.5h;

6-nitrobenzo[d]thiazole; In tetrahydrofuran; at -20 ℃; for 2h;

With sodium tetrahydroborate; iron(II) chloride; In tetrahydrofuran; ethanol; at 20 ℃; for 2h; Further stages.;

DOI:10.1021/ja026718r

upstream raw materials:

4-iodobenzoic acid ethyl ester

6-nitrobenzo[d]thiazole

Refernces