N-De[2-(Methylsulfonyl)ethyl] Lapatinib

Base Information

Chemical Name:N-De[2-(Methylsulfonyl)ethyl] Lapatinib
CAS No.:697299-82-4
Molecular Formula:C26H20ClFN4O2
Molecular Weight:474.922
Hs Code.:
Mol file:697299-82-4.mol

Synonyms:N-De[2-(Methylsulfonyl)ethyl] Lapatinib;[6-(5-AMinoMethylfuran-2-yl)quinazolin-4-yl][3-chloro- 4-(3-fluorobenzyloxy)phenyl]aMine;6-[5-(AMinoMethyl)-2-furanyl]-N-[3-chloro-4-[(3-fluorophenyl)Methoxy]phenyl]-4-quinazolinaMine

Suppliers and Price of N-De[2-(Methylsulfonyl)ethyl] Lapatinib

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-De[2-(methylsulfonyl)ethyl]Lapatinib
5mg
$ 215.00

Biosynth Carbosynth
N-De[2-(methylsulfonyl)ethyl] lapatinib
10 mg
$ 1050.00

Biosynth Carbosynth
N-De[2-(methylsulfonyl)ethyl] lapatinib
5 mg
$ 650.00

Biosynth Carbosynth
N-De[2-(methylsulfonyl)ethyl] lapatinib
2 mg
$ 324.00

Total 10 raw suppliers

Chemical Property of N-De[2-(Methylsulfonyl)ethyl] Lapatinib

Chemical Property:

Boiling Point:626.4±55.0 °C(Predicted)
PKA:8.83±0.29(Predicted)
PSA：86.20000
Density:1.376±0.06 g/cm3(Predicted)
LogP:7.23690
Storage Temp.:-20°C Freezer, Under inert atmosphere
Solubility.:DMSO (Slightly), Methanol (Slightly, Heated)

Purity/Quality:

NLT 98% ^*data from raw suppliers

N-De[2-(methylsulfonyl)ethyl]Lapatinib ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses A reactive metabolite of Lapatinib (L175800) which is associated with various drug toxicities. Lapatinib is metabolized mainly by P450 3A4 to form O- and N-dealkylated metabolites.

Technology Process of N-De[2-(Methylsulfonyl)ethyl] Lapatinib

There total 2 articles about N-De[2-(Methylsulfonyl)ethyl] Lapatinib which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%