CHEMBRDG-BB 9071633

Base Information

• Chemical Name: CHEMBRDG-BB 9071633
• CAS No.: 93189-07-2
• Molecular Formula: C13H13NO
• Molecular Weight: 199.252
• Hs Code.: 2922299090
• Mol file: 93189-07-2.mol

Synonyms:CHEMBRDG-BB 9071633;3-(ANILINOMETHYL)PHENOL;UKRORGSYN-BB BBV-118836;3-(anilinomethyl)phenol(SALTDATA: FREE)

Chemical Property of CHEMBRDG-BB 9071633

Chemical Property:

• Vapor Pressure: 3.92E-06mmHg at 25°C
• Boiling Point: 374.3°C at 760 mmHg
• Flash Point: 163.3°C
• PSA: 32.26000
• Density: 1.185g/cm³
• LogP: 3.07730

Purity/Quality:

3-(ANILINOMETHYL)PHENOL 95.00% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CHEMBRDG-BB 9071633

There total 5 articles about CHEMBRDG-BB 9071633 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

N-(m-hydroxybenzylidene)aniline (13206-60-5,41097-59-0) → N-(3-hydroxybenzyl)benzenamine (93189-07-2)

Guidance literature:

With diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; In dichloromethane; at 20 ℃; for 15h;

DOI:10.1055/s-2007-980349

Reference yield: 73.5%

3-hydroxy-N-phenyl-benzamide (27559-45-1) → N-(3-hydroxybenzyl)benzenamine (93189-07-2)

Guidance literature:

3-hydroxy-N-phenyl-benzamide; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 1h; Heating / reflux;

With water; ammonium chloride; In tetrahydrofuran; diethyl ether; at 20 ℃;

Reference yield:

meta-hydroxybenzaldehyde (100-83-4) → N-(3-hydroxybenzyl)benzenamine (93189-07-2)

Guidance literature:

Multi-step reaction with 2 steps

1: water / 35 - 40 °C

2: sodium amalgam; alcohol

With sodium amalgam; ethanol; water;

upstream raw materials:

N-(3-Hydroxy-benzyl)-N-phenyl-formamide

N-(m-hydroxybenzylidene)aniline

meta-hydroxybenzaldehyde

3-hydroxy-N-phenyl-benzamide

Downstream raw materials:

4-chloro-3-(3-phenylaminomethyl-phenoxymethyl)-thieno[3,2-c]pyridine-7-carboxylic acid ethyl ester

methyl 4-((3-((phenylamino)methyl)phenoxy)-methyl)benzoate