3-Fluoroisoquinoline

Base Information

• Chemical Name: 3-Fluoroisoquinoline
• CAS No.: 396-29-2
• Molecular Formula: C9H6FN
• Molecular Weight: 147.1490432
• Hs Code.: 2933499090
• Mol file: 396-29-2.mol

Synonyms:3-Fluoroisoquinoline

Chemical Property of 3-Fluoroisoquinoline

Chemical Property:

• Vapor Pressure: 0.015mmHg at 25°C
• Boiling Point: 266.047°C at 760 mmHg
• Flash Point: 114.701°C
• Density: 1.216g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

3-Fluoroisoquinoline 95.0% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Fluoroisoquinoline

There total 1 articles about 3-Fluoroisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3-fluoroisoquinoline (396-29-2)

Guidance literature:

DOI:10.1021/ja01146a054

Reference yield:

3-fluoroisoquinoline (396-29-2) → C18H13FN4O

Guidance literature:

Multi-step reaction with 4 steps

1: aluminum (III) chloride / dichloromethane / 40 °C

2: hydrazine / methanol / 60 °C

3: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 60 °C

4: N-ethyl-N,N-diisopropylamine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate / N,N-dimethyl-formamide / 20 °C

With aluminum (III) chloride; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; hydrazine; In methanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2013.09.055

Reference yield:

3-fluoroisoquinoline (396-29-2) → 3-fluoro-5-isoquinolinamine (581813-05-0)

Guidance literature:

Downstream raw materials:

3-fluoro-5-isoquinolinamine