Pyrazolo[1,5-a]pyrimidine-6-carboxylic acid, 7-amino-3-methyl- (7CI)

Base Information

• Chemical Name: Pyrazolo[1,5-a]pyrimidine-6-carboxylic acid, 7-amino-3-methyl- (7CI)
• CAS No.: 89977-62-8
• Molecular Formula: C₈H₈N₄O₂
• Molecular Weight: 192.177
• Hs Code.: 2933990090
• Mol file: 89977-62-8.mol

Synonyms:Pyrazolo[1,5-a]pyrimidine-6-carboxylic acid, 7-amino-3-methyl- (7CI);Pyrazolo[1,5-a]pyriMidine-6-carboxylic acid, 7-aMino-3-Methyl;7-AMino-3-Methylpyrazolo[1,5-a]pyriMidine-6-carboxylic acid

Chemical Property of Pyrazolo[1,5-a]pyrimidine-6-carboxylic acid, 7-amino-3-methyl- (7CI)

Chemical Property:

• PSA: 93.51000
• LogP: 0.89930
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

7-Amino-3-methylpyrazolo[1,5-a]pyrimidine-6-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Pyrazolo[1,5-a]pyrimidine-6-carboxylic acid, 7-amino-3-methyl- (7CI)

There total 2 articles about Pyrazolo[1,5-a]pyrimidine-6-carboxylic acid, 7-amino-3-methyl- (7CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

7-amino-3-methyl-pyrazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester (2755-44-4) → 7-amino-3-methyl-pyrazolo[1,5-a]pyrimidine-6-carboxylic acid (89977-62-8)

Guidance literature:

With sodium hydroxide; In ethanol; for 4h; Reflux;

DOI:10.1016/j.bmcl.2015.11.093

Reference yield:

→ 7-amino-3-methyl-pyrazolo[1,5-a]pyrimidine-6-carboxylic acid (89977-62-8)

Guidance literature:

3-Methyl-7-amino-pyrazolo<1.5-a>pyrimidin-6-carbonsaeure-ethylester,Δ,wss.HCl;

Reference yield:

3-methoxy-1-iodobenzene (766-85-8) + 7-amino-3-methyl-pyrazolo[1,5-a]pyrimidine-6-carboxylic acid (89977-62-8) → C15H14N4O3

Guidance literature:

With copper(l) iodide; potassium carbonate; L-proline; In N,N-dimethyl-formamide; at 110 ℃; for 2h; Microwave irradiation;

DOI:10.1016/j.bmcl.2015.11.093

upstream raw materials:

7-amino-3-methyl-pyrazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester

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