(S)-benzyl 2-(5-(4-bromophenyl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate

Base Information

Chemical Name:(S)-benzyl 2-(5-(4-bromophenyl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
CAS No.:1007882-39-4
Molecular Formula:C21H20BrN3O2
Molecular Weight:426.313
Hs Code.:

Synonyms:(S)-benzyl 2-(5-(4-bromophenyl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate

Suppliers and Price of (S)-benzyl 2-(5-(4-bromophenyl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-benzyl 2-(5-(4-bromophenyl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate

Chemical Property:

PSA：58.22000
LogP:5.25080

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (S)-benzyl 2-(5-(4-bromophenyl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate

There total 5 articles about (S)-benzyl 2-(5-(4-bromophenyl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1180671-39-9
1-benzyl-2-[2-(4-bromophenyl)-2-oxoethyl] (2S)-pyrrolidine-1,2-dicarboxylate

: 1007882-39-4
(S)-benzyl 2-(5-(4-bromophenyl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate

Guidance literature:: With ammonium acetate; In xylene; at 150 ℃; for 5h;

Reference yield:

: 99-73-0,132309-76-3
para-bromophenacyl bromide

: 1148-11-4
N-Benzyloxycarbonyl-L-proline

: 1007882-39-4
(S)-benzyl 2-(5-(4-bromophenyl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate

Guidance literature:: para-bromophenacyl bromide; N-Benzyloxycarbonyl-L-proline; With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 20 ℃; for 1.5h;

With ammonium acetate; In toluene; at 100 ℃; for 16.5h;

With sodium hydrogencarbonate; In water; toluene; at 20 ℃; pH=~ 9;

Reference yield:

: 1148-11-4
N-Benzyloxycarbonyl-L-proline

: 1007882-39-4
(S)-benzyl 2-(5-(4-bromophenyl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / dichloromethane / 16 h / 0 - 20 °C

2: ammonium acetate / xylene / 5 h / 150 °C

With ammonium acetate; N-ethyl-N,N-diisopropylamine; In dichloromethane; xylene;