5-bromonaphtho[2,1-b][1]benzothiole

Base Information

• Chemical Name: 5-bromonaphtho[2,1-b][1]benzothiole
• CAS No.: 189097-35-6
• Molecular Formula: C16H9BrS
• Molecular Weight: 313.21
• Mol file: 189097-35-6.mol

Synonyms:5-bromonaphtho[2,1-b][1]benzothiole;5-Bromobenzo[b]naphtho[1,2-d]thiophene;Benzo[b]naphtho[1,2-d]thiophene, 5-bromo-

Chemical Property of 5-bromonaphtho[2,1-b][1]benzothiole

Chemical Property:

• Melting Point: 163 °C
• PSA: 28.24000
• LogP: 5.97020

Purity/Quality:

97% ^*data from raw suppliers

5-Bromobenzo[b]naphtho[1,2-d]thiophene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-bromonaphtho[2,1-b][1]benzothiole

There total 5 articles about 5-bromonaphtho[2,1-b][1]benzothiole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

Benzo[b]naphtho[1,2-d]thiophene (205-43-6) → 5-bromobenzo[b]naphtha[1,2-d]thiophene (189097-35-6)

Guidance literature:

With bromine; In dichloromethane; at 0 ℃;

Reference yield:

(2-(methylthio)naphthalene-1-yl)boronic acid → 5-bromobenzo[b]naphtha[1,2-d]thiophene (189097-35-6)

Guidance literature:

Multi-step reaction with 4 steps

1.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / toluene; ethanol; water / 3.5 h / 80 °C

2.1: acetic acid; dihydrogen peroxide / 10 h / 0 - 20 °C

3.1: phosphorus pentoxide; trifluorormethanesulfonic acid / 24 h / 20 °C

3.2: 12 h / Reflux

4.1: N-Bromosuccinimide / dichloromethane / 2 h / 20 °C

With N-Bromosuccinimide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; trifluorormethanesulfonic acid; phosphorus pentoxide; dihydrogen peroxide; potassium carbonate; acetic acid; In ethanol; dichloromethane; water; toluene;

Reference yield:

bromobenzene (108-86-1,52753-63-6) → 5-bromobenzo[b]naphtha[1,2-d]thiophene (189097-35-6)

Guidance literature:

Multi-step reaction with 4 steps

1.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / toluene; ethanol; water / 3.5 h / 80 °C

2.1: acetic acid; dihydrogen peroxide / 10 h / 0 - 20 °C

3.1: phosphorus pentoxide; trifluorormethanesulfonic acid / 24 h / 20 °C

3.2: 12 h / Reflux

4.1: N-Bromosuccinimide / dichloromethane / 2 h / 20 °C

With N-Bromosuccinimide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; trifluorormethanesulfonic acid; phosphorus pentoxide; dihydrogen peroxide; potassium carbonate; acetic acid; In ethanol; dichloromethane; water; toluene;

upstream raw materials:

Benzo[b]naphtho[1,2-d]thiophene

bromobenzene

Downstream raw materials:

C₂₂H₁₃NS

14H-benzo[c]benzo[4,5]thieno[2,3-a]carbazole