2-(2-Butenylthio)-2-ethylbutyramide

Base Information

• Chemical Name: 2-(2-Butenylthio)-2-ethylbutyramide
• CAS No.: 66859-52-7
• Molecular Formula: C10H19NOS
• Molecular Weight: 201.329
• Nikkaji Number: J65.816B
• Wikidata: Q76326500
• Mol file: 66859-52-7.mol

Synonyms:2-(2-Butenylthio)-2-ethylbutyramide;BRN 1707069;66859-52-7;BUTYRAMIDE, 2-(2-BUTENYLTHIO)-2-ETHYL-;Butanamide, 2-(2-butenylthio)-2-ethyl-;LS-47587

Chemical Property of 2-(2-Butenylthio)-2-ethylbutyramide

Chemical Property:

• Vapor Pressure: 0.00023mmHg at 25°C
• Boiling Point: 325.5°Cat760mmHg
• Flash Point: 150.6°C
• PSA: 69.38000
• Density: 0.996g/cm³
• LogP: 3.48950
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 201.11873540
• Heavy Atom Count: 13
• Complexity: 185

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(CC)(C(=O)N)SCC=CC
• Isomeric SMILES: CCC(CC)(C(=O)N)SC/C=C/C

Technology Process of 2-(2-Butenylthio)-2-ethylbutyramide

There total 6 articles about 2-(2-Butenylthio)-2-ethylbutyramide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Buten-(2)-ylmercapto-2-ethyl-buttersaeure-chlorid (90976-95-7) → 2-Buten-(2)-ylmercapto-2-ethyl-buttersaeure-amid (66859-52-7)

Guidance literature:

With ammonia; In diethyl ether;

DOI:10.1021/jm00340a003

Reference yield:

2-mercapto-2-ethylbutyric acid (52988-77-9) → 2-Buten-(2)-ylmercapto-2-ethyl-buttersaeure-amid (66859-52-7)

Guidance literature:

Multi-step reaction with 3 steps

1: (i) NaOEt, EtOH, (ii) 1-halo-but-2-ene

2: SOCl₂

3: NH₃ / diethyl ether

With thionyl chloride; ammonia; In diethyl ether;

DOI:10.1021/jm00340a003

Reference yield:

2-Buten-(2)-ylmercapto-2-ethyl-buttersaeure (91140-36-2) → 2-Buten-(2)-ylmercapto-2-ethyl-buttersaeure-amid (66859-52-7)

Guidance literature:

Multi-step reaction with 2 steps

1: SOCl₂

2: NH₃ / diethyl ether

With thionyl chloride; ammonia; In diethyl ether;

DOI:10.1021/jm00340a003

upstream raw materials:

2-ethyl-2-but-2t-enylmercapto-butyryl chloride

2-Buten-⁽²⁾-ylmercapto-2-ethyl-buttersaeure-chlorid

2-ethyl-2-but-2t-enylmercapto-butyric acid

2-mercapto-2-ethylbutyric acid