3-Hydroxy-benzoic acid 1,1′-(3-fluoro-1,2-phenylene) ester

Base Information

Chemical Name:3-Hydroxy-benzoic acid 1,1′-(3-fluoro-1,2-phenylene) ester
CAS No.:1223397-11-2
Molecular Formula:C20H13FO6
Molecular Weight:368.31
Hs Code.:
Mol file:1223397-11-2.mol

Synonyms:3-Fluoro-1,2-phenylene bis(3-hydroxybenzoate);3-Hydroxy-benzoic acid 1,1′-(3-fluoro-1,2-phenylene) ester;WZB-117

Suppliers and Price of 3-Hydroxy-benzoic acid 1,1′-(3-fluoro-1,2-phenylene) ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
WZB117
50mg
$ 230.00

TRC
WZB117
10mg
$ 65.00

TRC
WZB117
25mg
$ 130.00

TRC
WZB117
100mg
$ 450.00

Tocris
WZB117 ≥98%(HPLC)
25
$ 335.00

Tocris
WZB117 ≥98%(HPLC)
5
$ 87.00

Sigma-Aldrich
Glucose Transporter Inhibitor IV, WZB117
25mg
$ 200.00

Sigma-Aldrich
WZB-117 ≥98% (HPLC)
5mg
$ 103.00

Sigma-Aldrich
WZB-117 ≥98% (HPLC)
25mg
$ 436.00

DC Chemicals
WZB117 >98%
250 mg
$ 900.00

Total 20 raw suppliers

Chemical Property of 3-Hydroxy-benzoic acid 1,1′-(3-fluoro-1,2-phenylene) ester

Chemical Property:

PSA：93.06000
LogP:3.67530
Storage Temp.:2-8°C
Solubility.:DMSO: soluble20mg/mL, clear

Purity/Quality:

99%, ^*data from raw suppliers

WZB117 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:N
Statements: 50
Safety Statements: 61

MSDS Files:

Useful:

Description WZB117 (1223397-11-2) is an inhibitor of Glucose Transporter 1 (GLUT1). It inhibited cell proliferation in lung cancer A549 cells and breast cancer MCF7 cells with an IC50 of approximately 10 μM. Daily intraperitoneal injection of WZB117 at 10mg/kg resulted in 70% reduction in tumor volume of human A549 lung cancer grafted on nude mice.
Uses WZB 117 is a GLUT1 inhibitor. WZB-117 has been used to study its tumor initiating ability in cancer stem cells. It has also been used to study the effect of glucose antagonists on 2-NBDG (2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose) uptake.

Technology Process of 3-Hydroxy-benzoic acid 1,1′-(3-fluoro-1,2-phenylene) ester

There total 2 articles about 3-Hydroxy-benzoic acid 1,1′-(3-fluoro-1,2-phenylene) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: