Technology Process of 3',6,7-Trimethoxy-4',5'-methylenedioxyisoflavone
There total 6 articles about 3',6,7-Trimethoxy-4',5'-methylenedioxyisoflavone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
2-Picolinic acid; copper(l) iodide; potassium carbonate;
In
N,N-dimethyl-formamide;
at 135 - 140 ℃;
for 8h;
DOI:10.1021/acs.jnatprod.6b00173
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium hydroxide / ethanol / 6 h / 20 °C
2: sodium hydroxide; dihydrogen peroxide / ethanol / 57 h / 20 - 30 °C
3: boron trifluoride diethyl etherate / dichloromethane / 3 h / 20 °C / Inert atmosphere
4: copper(l) iodide; potassium carbonate; 2-Picolinic acid / N,N-dimethyl-formamide / 8 h / 135 - 140 °C
With
2-Picolinic acid; copper(l) iodide; boron trifluoride diethyl etherate; dihydrogen peroxide; potassium carbonate; sodium hydroxide;
In
ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/acs.jnatprod.6b00173
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium hydroxide / 0.67 h / 100 °C
1.2: 15 °C
2.1: sodium hydroxide / ethanol / 6 h / 20 °C
3.1: sodium hydroxide; dihydrogen peroxide / ethanol / 57 h / 20 - 30 °C
4.1: boron trifluoride diethyl etherate / dichloromethane / 3 h / 20 °C / Inert atmosphere
5.1: copper(l) iodide; potassium carbonate; 2-Picolinic acid / N,N-dimethyl-formamide / 8 h / 135 - 140 °C
With
2-Picolinic acid; copper(l) iodide; boron trifluoride diethyl etherate; dihydrogen peroxide; potassium carbonate; potassium hydroxide; sodium hydroxide;
In
ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/acs.jnatprod.6b00173