Methyl 3-(2,4-dimethoxyphenyl)-3-oxopropanoate

Base Information

Chemical Name:Methyl 3-(2,4-dimethoxyphenyl)-3-oxopropanoate
CAS No.:676348-64-4
Molecular Formula:C12H14O5
Molecular Weight:238.24
Hs Code.:2918990090
DSSTox Substance ID:DTXSID101262212
Mol file:676348-64-4.mol

Synonyms:676348-64-4;methyl 3-(2,4-dimethoxyphenyl)-3-oxopropanoate;3-(2,4-Dimethoxy-phenyl)-3-oxo-propionic acid methyl ester;3-(2,4-dimethoxyphenyl)-3-oxo-propionic acidmethyl ester;SCHEMBL13515976;KYIVDZUWNQZWOH-UHFFFAOYSA-N;DTXSID101262212;BCB34864;AKOS002232415;Methyl 2,4-dimethoxy-beta-oxobenzenepropanoate;EN300-1828437;3-(2,4-dimethoxyphenyl)-3-oxo-propionic acid methyl ester;3-(2,4-dimethoxy-phenyl)-3-oxo-propionic acid methyl ester, AldrichCPR

Suppliers and Price of Methyl 3-(2,4-dimethoxyphenyl)-3-oxopropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

CHESS?
KM000151:3-(2,4-Dimethoxy-phenyl)-3-oxo-propionicacidmethylester 96
1 g
$ 276.00

American Custom Chemicals Corporation
3-(2,4-DIMETHOXYPHENYL)-3-OXO-PROPIONIC ACID METHYL ESTER 98.00%
1G
$ 1068.38

AHH
3-(2,4-Dimethoxyphenyl)-3-oxo-propionicacidmethylester 98%
1g
$ 270.00

Total 5 raw suppliers

Chemical Property of Methyl 3-(2,4-dimethoxyphenyl)-3-oxopropanoate

Chemical Property:

PSA：61.83000
LogP:1.44960
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:238.08412354
Heavy Atom Count:17
Complexity:276

Purity/Quality:

99% ^*data from raw suppliers

KM000151:3-(2,4-Dimethoxy-phenyl)-3-oxo-propionicacidmethylester 96 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=C(C=C1)C(=O)CC(=O)OC)OC

Technology Process of Methyl 3-(2,4-dimethoxyphenyl)-3-oxopropanoate

There total 2 articles about Methyl 3-(2,4-dimethoxyphenyl)-3-oxopropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 37517-81-0
3-chloro-3-oxopropanoic acid methyl ester

: 151-10-0
1,3-Dimethoxybenzene

: 676348-64-4
methyl 3-(2,4-dimethoxyphenyl)-3-oxopropanoate

Guidance literature:: With aluminum (III) chloride; In dichloromethane; at 0 - 20 ℃; chemoselective reaction;
DOI:10.1055/s-0035-1561370

Reference yield: 85.0%

: 829-20-9
2',4'-dimethoxyacetophenone

: 616-38-6
carbonic acid dimethyl ester

: 676348-64-4
methyl 3-(2,4-dimethoxyphenyl)-3-oxopropanoate

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran; tert-butyl methyl ether; at 20 ℃; Inert atmosphere;

Reference yield: 94.0%

: 62-53-3
aniline

: 676348-64-4
methyl 3-(2,4-dimethoxyphenyl)-3-oxopropanoate

: methyl 3-(2,4-dimethoxyphenyl)-3-oxo-2-(2-phenylhydrazono)-propanoate

Guidance literature:: aniline; With hydrogenchloride; sodium nitrite; In water; at 0 ℃; for 1h;

methyl 3-(2,4-dimethoxyphenyl)-3-oxopropanoate; With potassium acetate; In 1,4-dioxane; methanol; at 0 - 20 ℃; for 1.45h;
DOI:10.1002/ejoc.201600178