3,3-DIMETHYL-PYRROLIDINE HYDROCHLORIDE

Base Information

• Chemical Name: 3,3-DIMETHYL-PYRROLIDINE HYDROCHLORIDE
• CAS No.: 792915-20-9
• Molecular Formula: C6H13N.ClH
• Molecular Weight: 135.637
• Hs Code.: 2933990090
• Mol file: 792915-20-9.mol

Synonyms:3,3-DIMETHYL-PYRROLIDINE HYDROCHLORIDE;3,3-DiMethylpyrrolidine hydrochlorid;3,3-DiMethylpyrrolidine HCl

Chemical Property of 3,3-DIMETHYL-PYRROLIDINE HYDROCHLORIDE

Chemical Property:

• PSA: 12.03000
• LogP: 2.13670
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

3,3-dimethylpyrrolidinehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,3-DIMETHYL-PYRROLIDINE HYDROCHLORIDE

There total 5 articles about 3,3-DIMETHYL-PYRROLIDINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-Benzyl-3,3-dimethylpyrrolidine (73434-00-1) → 3,3-dimethylpyrrolidine hydrochloride (792915-20-9)

Guidance literature:

1-Benzyl-3,3-dimethylpyrrolidine; With hydrogen; palladium 10% on activated carbon; In methanol; phosphorus pentoxide; for 72h; under 22502.3 Torr;

With hydrogenchloride; In diethyl ether;

Reference yield:

3,3-dimethylpyrrolidine-2,5-dione (3437-29-4) → 3,3-dimethylpyrrolidine hydrochloride (792915-20-9)

Guidance literature:

3,3-dimethylpyrrolidine-2,5-dione; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 12h; Heating / reflux;

With sodium hydroxide; In tetrahydrofuran; water; at 0 ℃; for 0.5h;

With hydrogenchloride; In diethyl ether; at 0 ℃; for 1h;

Reference yield:

tert-butyl 3,3-dimethylpyrrolidine-1-carboxylate (851429-33-9) → 3,3-dimethylpyrrolidine hydrochloride (792915-20-9)

Guidance literature:

With hydrogenchloride; In diethyl ether; at 20 ℃; for 2h;

upstream raw materials:

3,3-dimethylpyrrolidine-2,5-dione

tert-butyl 3,3-dimethylpyrrolidine-1-carboxylate

2,2-dimethylsuccinic acid

1-benzyl-3,3-dimethylpyrrolidine-2,5-dione

Downstream raw materials:

N-(3-(5-chloro-2-methoxyphenyl)-1-(2-(3,3-dimethylpyrrolidin-1-yl)-2-oxoethyl)-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

N-(6-(3,3-dimethylpyrrolidin-1-yl)pyridin-2-yl)-6-phenylimidazo[1,2-b]pyridazin-8-amine

methyl 3-(8-(6-(3,3-dimethylpyrrolidin-1-yl)pyridin-2-ylamino)imidazo[1,2-b]pyridazin-6-yl)benzoate

(S)-2-(tert-butoxy)-2-(7-(3,3-dimethylpyrrolidin-1-yl)-5-methyl-2-phenylpyrazolo[1,5-a]pyrimidin-6-yl)acetic acid

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