2-Chloro-6-methyl-3-phenylquinoline

Base Information

• Chemical Name: 2-Chloro-6-methyl-3-phenylquinoline
• CAS No.: 284664-59-1
• Molecular Formula: C16H12ClN
• Molecular Weight: 253.73
• Hs Code.: 2933499090
• European Community (EC) Number: 803-455-0
• DSSTox Substance ID: DTXSID50381811
• Wikidata: Q82172888
• ChEMBL ID: CHEMBL1603164
• Mol file: 284664-59-1.mol

Synonyms:2-chloro-6-methyl-3-phenylquinoline;284664-59-1;MLS001143867;CHEMBL1603164;DTXSID50381811;HMS2805K15;MFCD00126763;SMR000473306;FT-0728750;2-Chloro-6-methyl-3-phenylquinoline, AldrichCPR

Chemical Property of 2-Chloro-6-methyl-3-phenylquinoline

Chemical Property:

• Vapor Pressure: 1.18E-05mmHg at 25°C
• Boiling Point: 380.6°C at 760 mmHg
• Flash Point: 215.9°C
• PSA: 12.89000
• Density: 1.206g/cm³
• LogP: 4.86360
• XLogP3: 5.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 253.0658271
• Heavy Atom Count: 18
• Complexity: 274

Purity/Quality:

98%Min ^*data from raw suppliers

2-Chloro-6-methyl-3-phenylquinoline Aldrich ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22-41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC2=CC(=C(N=C2C=C1)Cl)C3=CC=CC=C3

Technology Process of 2-Chloro-6-methyl-3-phenylquinoline

There total 1 articles about 2-Chloro-6-methyl-3-phenylquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

C16H13NO (1200688-18-1) → C16H12ClN (284664-59-1)

Guidance literature:

C₁₆H₁₃NO; With N-ethyl-N,N-diisopropylamine; trichlorophosphate; In dichloromethane; at 0 ℃; Inert atmosphere;

With tetrabutyl-ammonium chloride; In dichloromethane; at 40 ℃; for 24h; Inert atmosphere;

DOI:10.1016/j.tetlet.2009.09.096

upstream raw materials:

C₁₆H₁₃NO

Refernces