1-(indol-4-yloxy)-3-(1-(4-azido-3-iodophenyl)-2-isobutylamine)-2-propanol

Base Information

Chemical Name:1-(indol-4-yloxy)-3-(1-(4-azido-3-iodophenyl)-2-isobutylamine)-2-propanol
CAS No.:77890-09-6
Molecular Formula:C₂₁H₂₄IN₅O₂
Molecular Weight:505.358
Hs Code.:
Mol file:77890-09-6.mol

Synonyms:2-Propanol,1-[[2-(4-azido-3-iodophenyl)-1,1-dimethylethyl]amino]-3-(1H-indol-4-yloxy)-, (?à)-; Iodoazidobenzylpindolol

Suppliers and Price of 1-(indol-4-yloxy)-3-(1-(4-azido-3-iodophenyl)-2-isobutylamine)-2-propanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of 1-(indol-4-yloxy)-3-(1-(4-azido-3-iodophenyl)-2-isobutylamine)-2-propanol

Chemical Property:

Melting Point:70-73 °C
PSA：107.03000
LogP:4.90856

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of 1-(indol-4-yloxy)-3-(1-(4-azido-3-iodophenyl)-2-isobutylamine)-2-propanol

There total 5 articles about 1-(indol-4-yloxy)-3-(1-(4-azido-3-iodophenyl)-2-isobutylamine)-2-propanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.8%

: 35308-87-3
4-(oxiranylmethoxy)-1H-indole

: 81530-24-7
1,1-dimethyl-2-(4-azido-3-iodophenyl)ethylamine

: 77890-09-6
DL-iodoazidobenzylpindolol

Guidance literature:: In ethanol; at 60 ℃; for 168h;
DOI:10.1002/jps.2600710310

Reference yield:

: 2380-94-1
1H-indol-4-ol

: 77890-09-6
DL-iodoazidobenzylpindolol

Guidance literature:: Multi-step reaction with 2 steps

1: 55.5 percent / aq. NaOH / 22 h / Ambient temperature

2: 78.8 percent / ethanol / 168 h / 60 °C

With sodium hydroxide; In ethanol;
DOI:10.1002/jps.2600710310

Reference yield:

: 5440-67-5
2-(4-nitrobenzyl)-2-nitropropane

: 77890-09-6
DL-iodoazidobenzylpindolol

Guidance literature:: Multi-step reaction with 4 steps

1: 48 percent / Zn, aq. HCl / ethanol; H₂O / Heating

2: 37 percent / NaI, thallium trichloride / H₂O / 1 h / Heating; pH 4.0

3: 1.) sodium nitrite, sulfuric acid (96percent), 2.) NaN₃ / 1) water, 15 min, 0 - 5 deg C; 2) water, 15 min

4: 78.8 percent / ethanol / 168 h / 60 °C

With hydrogenchloride; sodium azide; thallium(III) chloride; sulfuric acid; sodium iodide; zinc; sodium nitrite; In ethanol; water;
DOI:10.1002/jps.2600710310