3-aMino-oxetane-3-carboxylic acid Methyl ester

Base Information

• Chemical Name: 3-aMino-oxetane-3-carboxylic acid Methyl ester
• CAS No.: 1363383-31-6
• Molecular Formula: C5H9NO3
• Molecular Weight: 131.131
• Hs Code.: 2932990090
• Mol file: 1363383-31-6.mol

Synonyms:3-aMino-oxetane-3-carboxylic acid Methyl ester;3-Oxetanecarboxylic acid, 3-amino-, methyl ester

Chemical Property of 3-aMino-oxetane-3-carboxylic acid Methyl ester

Chemical Property:

• Boiling Point: 165.9±40.0 °C(Predicted)
• PKA: 3.91±0.20(Predicted)
• PSA: 61.55000
• Density: 1.241±0.06 g/cm3(Predicted)
• LogP: -0.41260
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

methyl3-aminooxetane-3-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-aMino-oxetane-3-carboxylic acid Methyl ester

There total 1 articles about 3-aMino-oxetane-3-carboxylic acid Methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C19H21NO3 (1452228-33-9) → methyl 3-aminooxetane-3-carboxylate (1363383-31-6)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 9h; under 2585.81 Torr;

Reference yield: 71.5%

methyl 3-aminooxetane-3-carboxylate (1363383-31-6) + ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphoric acid monophenyl ester (379270-35-6) → C20H25N6O6P

Guidance literature:

With thionyl chloride; In acetonitrile; at 80 ℃; for 6h; pH=6 - 7;

Reference yield: 62.0%

N-(Benzyloxycarbonyloxy)succinimide (13139-17-8) + methyl 3-aminooxetane-3-carboxylate (1363383-31-6) → methyl 3-(benzyloxycarbonylamino)oxetane-3-carboxylate

Guidance literature:

With sodium hydrogencarbonate; In tetrahydrofuran; water; at 0 - 22 ℃; for 24h;

upstream raw materials:

C₁₉H₂₁NO₃

Refernces

• 1、 -. "DIHYDROPTERIDINONES II". Page/Page column 76; 77. . Retrieved 2014/09/03.