1-Benzyl-piperidine-3,3,5,5-d4-4-ol

Base Information

Chemical Name:1-Benzyl-piperidine-3,3,5,5-d4-4-ol
CAS No.:88227-11-6
Molecular Formula:C₁₂H₁₇NO
Molecular Weight:195.241
Hs Code.:
Mol file:88227-11-6.mol

Synonyms:1-Benzyl-piperidine-3,3,5,5-d4-4-ol;1-Benzyl-4-piperidinol-3,3,5,5-d4;1-(PhenylMethyl)-4-piperidin-3,3,5,5-d4-ol;1-(PhenylMethyl)-4-piperidinol-d4;4-Hydroxy-1-benzylpiperidine-d4;4-Hydroxy-N-benzylpiperidine-d4;N-Benzyl-4-hydroxypiperidine-d4;NSC 72991-d4

Suppliers and Price of 1-Benzyl-piperidine-3,3,5,5-d4-4-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Benzyl-4-piperidinol-3,3,5,5-d4
10mg
$ 155.00

Total 4 raw suppliers

Chemical Property of 1-Benzyl-piperidine-3,3,5,5-d4-4-ol

Chemical Property:

Vapor Pressure:0.001mmHg at 25°C
Boiling Point:294.409°C at 760 mmHg
Flash Point:123.519°C
PSA：23.47000
Density:1.13g/cm³
LogP:1.58120

Purity/Quality:

99% ^*data from raw suppliers

1-Benzyl-4-piperidinol-3,3,5,5-d4 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-Benzyl-piperidine-3,3,5,5-d4-4-ol

There total 2 articles about 1-Benzyl-piperidine-3,3,5,5-d4-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 88227-09-2
1-benzyl-4-piperidone-3,3,5,5-d₄

: 88227-11-6
1-benzyl-4-piperidinol-3,3,5,5-d₄

Guidance literature:: With lithium aluminium tetrahydride;
DOI:10.1002/omr.1270210904

Reference yield:

: 3612-20-2
1-phenylmethyl-4-piperidone

: 88227-11-6
1-benzyl-4-piperidinol-3,3,5,5-d₄

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / NaCl, Na₂CO₃ / D₂O / 5 h / 100 °C

2: 96 percent / lithium aluminum hydride

With lithium aluminium tetrahydride; sodium carbonate; sodium chloride; In water-d2;
DOI:10.1002/omr.1270210904

Reference yield:

: 88227-11-6
1-benzyl-4-piperidinol-3,3,5,5-d₄

: C₁₅H₁₇⁽²⁾H₃N₄O₅S

Guidance literature:: Multi-step reaction with 5 steps

1: 46 percent

2: 95 percent / potassium tert-butoxide / dimethylsulfoxide / 7 h / Ambient temperature

3: 84 percent / toluene / 18 h / Heating

4: 69 percent / m-chloroperbenzoic acid / CH₂Cl₂ / 15 h

5: 1.) sodium azide, ammonium chloride, 2.) pyridine / 1.) reflux, 15 h, aq. ethanol; 2.) 48 h

With pyridine; sodium azide; ammonium chloride; potassium tert-butylate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; dimethyl sulfoxide; toluene;
DOI:10.1002/omr.1270210904