Technology Process of 4-Piperidineaceticacid,2,2,6-trimethyl-,ethylester,trans-(+)-(8CI)
There total 3 articles about 4-Piperidineaceticacid,2,2,6-trimethyl-,ethylester,trans-(+)-(8CI) which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
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/BRN= 496404/ in verd. KOH, (200grad, 20h, Autoklav);
- Guidance literature:
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Trennung des Stereoisomerengemisches ueber Pikrate, Hydrochloride, neben entspr. (+-)-trans-Form; zers. des (+-)-cis-Hydrochlorids mit NaOC2H5-Lsg. bei 0grad, H2O-Auschluss;
- Guidance literature:
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cis/trans-Stereoisomerengemisches (s.bei der (+-)-cis-Form); freie Base aus (+-)-trans-Hydrochlorids mit NaOC2H5-Lsg. bei 0grad, H2O-Auschluss (Ausb.95percent);