Imidazo[1,2-d][1,2,4]triazin-8(7H)-one (9CI)

Base Information

Chemical Name:Imidazo[1,2-d][1,2,4]triazin-8(7H)-one (9CI)
CAS No.:689298-00-8
Molecular Formula:C₅H₄N₄O
Molecular Weight:136.113
Hs Code.:
Mol file:689298-00-8.mol

Synonyms:Imidazo[1,2-d][1,2,4]triazin-8(7H)-one (9CI);Imidazo[1,2-d][1,2,4]triazin-8(7H)-one

Suppliers and Price of Imidazo[1,2-d][1,2,4]triazin-8(7H)-one (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
Imidazo[1,2-D][1,2,4]triazin-8(7H)-one
5g
$ 2222.00

AK Scientific
Imidazo[1,2-D][1,2,4]triazin-8(7H)-one
250mg
$ 399.00

AccelPharmtech
Imidazo[1,2-d][1,2,4]triazin-8(7H)-one 97.00%
25G
$ 13300.00

AccelPharmtech
Imidazo[1,2-d][1,2,4]triazin-8(7H)-one 97.00%
5G
$ 5360.00

AccelPharmtech
Imidazo[1,2-d][1,2,4]triazin-8(7H)-one 97.00%
1G
$ 3120.00

Total 2 raw suppliers

Chemical Property of Imidazo[1,2-d][1,2,4]triazin-8(7H)-one (9CI)

Chemical Property:

PSA：63.05000
LogP:-0.58240

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Imidazo[1,2-D][1,2,4]triazin-8(7H)-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Imidazo[1,2-d][1,2,4]triazin-8(7H)-one (9CI)

There total 1 articles about Imidazo[1,2-d][1,2,4]triazin-8(7H)-one (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 4637-24-5
N,N-dimethyl-formamide dimethyl acetal

: 68251-67-2
imidazoyl acyl hydrazine

: 689298-00-8
7H-imidazo[1,2-d][1,2,4]triazin-8-one

Guidance literature:: In diphenylether; at 210 ℃;
DOI:10.1016/j.bmcl.2005.12.027

Reference yield:

: 689298-00-8
7H-imidazo[1,2-d][1,2,4]triazin-8-one

: 4,2'-difluoro-5'-(7-methyl-8-oxo-7,8-dihydroimidazo[1,2-d][1,2,4]triazin-3-yl)-biphenyl-2-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: NaH; LiBr / 60 °C

2: Pd(OAc)2; PPh₃; KOAc / N,N-dimethyl-acetamide / 120 °C

With palladium diacetate; potassium acetate; sodium hydride; triphenylphosphine; lithium bromide; In N,N-dimethyl acetamide; 2: Heck reaction;
DOI:10.1016/j.bmcl.2005.12.027

Reference yield:

: 689298-00-8
7H-imidazo[1,2-d][1,2,4]triazin-8-one

: 5'-(7-ethyl-8-oxo-7,8-dihydro-imidazo[1,2-d][1,2,4]triazin-3-yl)-4,2'-difluoro-biphenyl-2-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: NaH; LiBr / 60 °C

2: Pd(OAc)2; PPh₃; KOAc / N,N-dimethyl-acetamide / 120 °C

With palladium diacetate; potassium acetate; sodium hydride; triphenylphosphine; lithium bromide; In N,N-dimethyl acetamide; 2: Heck reaction;
DOI:10.1016/j.bmcl.2005.12.027