(+)-6-Dodecen-4-olide

Base Information

Chemical Name:(+)-6-Dodecen-4-olide
CAS No.:63357-98-2
Molecular Formula:C₁₂H₂₀O₂
Molecular Weight:196.29
Hs Code.:
DSSTox Substance ID:DTXSID401244108
Nikkaji Number:J61.246D
Wikidata:Q105219836

Synonyms:63357-98-2;(5S)-5-[(Z)-Oct-2-enyl]oxolan-2-one;(+)-6-Dodecen-4-olide;SCHEMBL18133543;DTXSID401244108;(s)-(+)-(z)-6-dodecen-4-olide;(5S)-Dihydro-5-(2Z)-2-octen-1-yl-2(3H)-furanone

Suppliers and Price of (+)-6-Dodecen-4-olide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (+)-6-Dodecen-4-olide

Chemical Property:

Boiling Point:311.2±11.0 °C(Predicted)
Density:0.950±0.06 g/cm3(Predicted)
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:196.146329876
Heavy Atom Count:14
Complexity:197

Purity/Quality:: 95%+ or 98%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCCCCC=CCC1CCC(=O)O1
Isomeric SMILES:CCCCC/C=C\C[C@@H]1CCC(=O)O1

Technology Process of (+)-6-Dodecen-4-olide

There total 6 articles about (+)-6-Dodecen-4-olide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 73697-60-6
ethyl 3-(oxiran-2-yl)propanoate

: 15456-69-6,60551-23-7,63357-98-2,63357-99-3,127127-84-8,18679-18-0
2(3H)-furanone, dihydro-5-(2-octenyl)-, (Z)-

Guidance literature:: In diethyl ether; 1.) -30 deg C --> -10 deg C, 1 h 2.) -10 deg C, 1h;
DOI:10.1016/0040-4020(80)80209-2

Reference yield:

: 1968-40-7
ethyl 4-pentenoate

: 15456-69-6,60551-23-7,63357-98-2,63357-99-3,127127-84-8,18679-18-0
2(3H)-furanone, dihydro-5-(2-octenyl)-, (Z)-

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / MCPBA / CH₂Cl₂

2: 88 percent / diethyl ether / 1.) -30 deg C --> -10 deg C, 1 h 2.) -10 deg C, 1h

With 3-chloro-benzenecarboperoxoic acid; In diethyl ether; dichloromethane;
DOI:10.1016/0040-4020(80)80209-2

Reference yield:

: 4762-26-9
hexyltriphenylphosphonium bromide

: 134359-16-3
γ-(prop-2-enyl)-γ-butyrolactone

: 15456-69-6,60551-23-7,63357-98-2,63357-99-3,127127-84-8,18679-18-0
2(3H)-furanone, dihydro-5-(2-octenyl)-, (Z)-

Guidance literature:: With n-butyllithium; hydrogen; ozone; palladium on activated charcoal; Yield given. Multistep reaction; 1.) EtOAc, -70 deg C; 2.) EtOAc, -10 deg C, then Rt; 3.) hexane, toluene, -70 deg C to Rt, 1 h;
DOI:10.1002/hlca.19820650204