methyl 4-(acetyloxy)-8-hydroxynaphthalene-2-carboxylate

Base Information

Chemical Name:methyl 4-(acetyloxy)-8-hydroxynaphthalene-2-carboxylate
CAS No.:181258-96-8
Molecular Formula:C₁₄H₁₂O₅
Molecular Weight:260.246
Hs Code.:
Mol file:181258-96-8.mol

Synonyms:2-Naphthalenecarboxylic acid, 4-(acetyloxy)-8-hydroxy-, Methyl ester

Suppliers and Price of methyl 4-(acetyloxy)-8-hydroxynaphthalene-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 2 raw suppliers

Chemical Property of methyl 4-(acetyloxy)-8-hydroxynaphthalene-2-carboxylate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:452.764°C at 760 mmHg
Flash Point:173.949°C
Density:1.318g/cm³

Purity/Quality:: 99% ，98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of methyl 4-(acetyloxy)-8-hydroxynaphthalene-2-carboxylate

There total 1 articles about methyl 4-(acetyloxy)-8-hydroxynaphthalene-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 144003-45-2
methyl 4-acetoxy-8-(phenylmethoxy)-2-naphthalenecarboxylate

: 181258-96-8
4-Acetoxy-8-hydroxy-naphthalene-2-carboxylic acid methyl ester

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; for 2.5h; under 1810.02 Torr;
DOI:10.1021/jm950699x

Reference yield:

: 181258-96-8
4-Acetoxy-8-hydroxy-naphthalene-2-carboxylic acid methyl ester

: 181258-99-1
4-Hydroxy-8-phenyl-naphthalene-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / 18 h / Ambient temperature

2: 86 percent / <(Ph₃P)3P>4Pd, K₃PO₄ / dioxane / 18 h / 85 °C

3: methanol. NaOMe / 1 h / Ambient temperature

With pyridine; potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium methylate; In 1,4-dioxane;
DOI:10.1021/jm950699x

Reference yield:

: 181258-96-8
4-Acetoxy-8-hydroxy-naphthalene-2-carboxylic acid methyl ester

: 181259-04-1
4-(2-Hydroxy-ethyl)-8-phenyl-naphthalene-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: pyridine / 18 h / Ambient temperature

2: 86 percent / <(Ph₃P)3P>4Pd, K₃PO₄ / dioxane / 18 h / 85 °C

3: methanol. NaOMe / 1 h / Ambient temperature

4: pyridine / CH₂Cl₂ / 1 h / 0 °C

5: 1.) LiCl, PdCl₂6H₅)3>2 / 1.) DMF, RT, 15 min, 2.) DMF, RT, 12 h

6: 1.) 9-BBN, 2.) aq. H₂O₂ / 1.) THF, RT, 48 h, 2.) THF, from 0 deg C to RT, 2 h

With pyridine; bis-triphenylphosphine-palladium(II) chloride; potassium phosphate; 9-borabicyclo[3.3.1]nonane dimer; tetrakis(triphenylphosphine) palladium⁽⁰⁾; dihydrogen peroxide; sodium methylate; lithium chloride; In 1,4-dioxane; dichloromethane;
DOI:10.1021/jm950699x