3β,16α-Dihydroxy-24-methylenelanosta-7,9(11)-dien-21-oic acid methyl ester

Base Information

• Chemical Name: 3β,16α-Dihydroxy-24-methylenelanosta-7,9(11)-dien-21-oic acid methyl ester
• CAS No.: 29505-28-0
• Molecular Formula: C32H50O4
• Molecular Weight: 498.737
• Mol file: 29505-28-0.mol

Synonyms:3β,16α-Dihydroxy-24-methylenelanosta-7,9(11)-dien-21-oic acid methyl ester;Methyl dehydrotumulosate

Chemical Property of 3β,16α-Dihydroxy-24-methylenelanosta-7,9(11)-dien-21-oic acid methyl ester

Chemical Property:

• Melting Point: 177 - 178 °C
• PSA: 66.76000
• LogP: 6.62500

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3β,16α-Dihydroxy-24-methylenelanosta-7,9(11)-dien-21-oic acid methyl ester

There total 3 articles about 3β,16α-Dihydroxy-24-methylenelanosta-7,9(11)-dien-21-oic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

polyporenate C de methyle (29556-92-1) → 3β,16α-dihydroxy-eburica-7,9(11),24(28)-trien-21-oic acid methyl ester (29505-28-0)

Guidance literature:

With 1,4-dioxane; sodium tetrahydroborate;

Reference yield:

polyporenic acid C (29556-93-2,38909-56-7,465-18-9) → 3β,16α-dihydroxy-eburica-7,9(11),24(28)-trien-21-oic acid methyl ester (29505-28-0)

Guidance literature:

Multi-step reaction with 2 steps

1: diazomethane

2: NaBH₄; aqueous dioxane

With diazomethane; 1,4-dioxane; sodium tetrahydroborate;

Reference yield:

→ (R)-2-((3S,10S,13R,14R,16R)-3,16-Dihydroxy-4,4,10,13,14-pentamethyl-2,3,4,5,6,10,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-6-methyl-5-methylene-heptanoic acid methyl ester (29505-28-0)

Guidance literature:

Verb. IV, Diazomethan;

DOI:10.1016/S0040-4039(01)98347-9

upstream raw materials:

polyporenate C de methyle

polyporenic acid C