L(+)-N-CBZ-ORNITHINE HYDROCHLORIDE

Base Information

• Chemical Name: L(+)-N-CBZ-ORNITHINE HYDROCHLORIDE
• CAS No.: 92455-59-9
• Molecular Formula: C13H19ClN2O4
• Molecular Weight: 302.75396
• Hs Code.: 2924299090
• Mol file: 92455-59-9.mol

Synonyms:L(+)-N-CBZ-ORNITHINE HYDROCHLORIDE ;(S)-5-Amino-2-benzyloxycarbonylamino-pentanoic acid hydrochloride;L(+)-N-Cbz-ornithine HCl

Chemical Property of L(+)-N-CBZ-ORNITHINE HYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 2.98E-11mmHg at 25°C
• Boiling Point: 510.7°C at 760 mmHg
• Flash Point: 262.6°C
• PSA: 101.65000
• LogP: 2.99810
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

Z-Orn-OH.HCl 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of L(+)-N-CBZ-ORNITHINE HYDROCHLORIDE

There total 3 articles about L(+)-N-CBZ-ORNITHINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Z-Orn(Boc)-OH (7733-29-1,199924-46-4) → Nα-benzyloxycarbonyl-L-ornithine hydrochloride (92455-59-9)

Guidance literature:

With hydrogenchloride; In water; acetone; for 1h; Heating;

Reference yield:

N-(Benzyloxycarbonyloxy)succinimide (13139-17-8) → Nα-benzyloxycarbonyl-L-ornithine hydrochloride (92455-59-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: Cu(CH₃COO)2; NaOH / H₂O; acetone / 44 h

1.2: 8-quinolinol; Na₂CO₃ / acetone; H₂O / 1.5 h

1.3: H₂O; acetone / 1.5 h / 20 °C

2.1: 22.76 g / HCl / acetone; H₂O / 1 h / Heating

With hydrogenchloride; sodium hydroxide; copper diacetate; In water; acetone;

Reference yield:

benzyl chloroformate (501-53-1,94274-21-2) → Nα-benzyloxycarbonyl-L-ornithine hydrochloride (92455-59-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: Na₂CO₃ / H₂O; acetone / 0.5 h / -10 °C

2.1: Cu(CH₃COO)2; NaOH / H₂O; acetone / 44 h

2.2: 8-quinolinol; Na₂CO₃ / acetone; H₂O / 1.5 h

2.3: H₂O; acetone / 1.5 h / 20 °C

3.1: 22.76 g / HCl / acetone; H₂O / 1 h / Heating

With hydrogenchloride; sodium hydroxide; copper diacetate; sodium carbonate; In water; acetone;

upstream raw materials:

Z-Orn(Boc)-OH

N-(Benzyloxycarbonyloxy)succinimide

benzyl chloroformate

Downstream raw materials:

N^α,N^ω,N^ω'-Tris(benzyloxycarbonyl)-L-arginin