4-Chloro-6-iodothieno[2,3-d]pyrimidine

Base Information

Chemical Name:4-Chloro-6-iodothieno[2,3-d]pyrimidine
CAS No.:552295-08-6
Molecular Formula:C6H2ClIN2S
Molecular Weight:296.52
Hs Code.:2934999090
European Community (EC) Number:819-499-9
Mol file:552295-08-6.mol

Synonyms:4-chloro-6-iodothieno[2,3-d]pyrimidine;552295-08-6;4-chloro-6-iodo-Thieno[2,3-d]pyrimidine;MFCD09746333;C6H2ClIN2S;SCHEMBL6484704;TQR0161;CIDKBLUFACXVRN-UHFFFAOYSA-N;AMY27447;CXA29508;CS-W000109;6-iodo4-chlorothieno[2,3-d]pyrimidine;6-iodo-4-chlorothieno[2,3-d]pyrimidine;DS-20175;SY213264;FT-0738388;EN300-262546;P17813;Z1269158922

Suppliers and Price of 4-Chloro-6-iodothieno[2,3-d]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
4-Chloro-6-iodothieno[2,3-d]pyrimidine 98.0%
250 mg
$ 730.00

SynQuest Laboratories
4-Chloro-6-iodothieno[2,3-d]pyrimidine 98.0%
100 mg
$ 399.00

SynQuest Laboratories
4-Chloro-6-iodothieno[2,3-d]pyrimidine 98.0%
1 g
$ 1909.00

Crysdot
4-Chloro-6-iodothieno[2,3-d]pyrimidine 97%
10g
$ 1935.00

Crysdot
4-Chloro-6-iodothieno[2,3-d]pyrimidine 97%
5g
$ 1340.00

Crysdot
4-Chloro-6-iodothieno[2,3-d]pyrimidine 97%
250mg
$ 174.00

Crysdot
4-Chloro-6-iodothieno[2,3-d]pyrimidine 97%
100mg
$ 109.00

Crysdot
4-Chloro-6-iodothieno[2,3-d]pyrimidine 97%
1g
$ 436.00

Chemenu
4-Chloro-6-iodothieno[2,3-d]pyrimidine 97%
1g
$ 411.00

Chemenu
4-Chloro-6-iodothieno[2,3-d]pyrimidine 97%
10g
$ 1823.00

Total 8 raw suppliers

Chemical Property of 4-Chloro-6-iodothieno[2,3-d]pyrimidine

Chemical Property:

Melting Point:168 °C
Boiling Point:369.1±37.0 °C(Predicted)
PKA:-0.26±0.40(Predicted)
PSA：54.02000
Density:2 +-.0.06 g/cm3(Predicted)
LogP:2.94930
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:295.86719
Heavy Atom Count:11
Complexity:160

Purity/Quality:

99%, ^*data from raw suppliers

4-Chloro-6-iodothieno[2,3-d]pyrimidine 98.0% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(SC2=C1C(=NC=N2)Cl)I

Technology Process of 4-Chloro-6-iodothieno[2,3-d]pyrimidine

There total 4 articles about 4-Chloro-6-iodothieno[2,3-d]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 6-iodo-3H-thieno[2, 3-d]pyrimidin-4-one

: 552295-08-6
4-chloro-6-iodo-thieno[2,3-d]pyrimidine

Guidance literature:: With N,N-dimethyl-aniline; trichlorophosphate; at 105 ℃; for 1h;
DOI:10.1021/acs.jmedchem.9b00134

Reference yield: 48.0%

: 14080-59-2
4-chlorothieno[2,3-d]pyrimidine

: 552295-08-6
4-chloro-6-iodo-thieno[2,3-d]pyrimidine

Guidance literature:: 4-chlorothieno[2,3-d]pyrimidine; With 2,2,6,6-tetramethyl-piperidine; n-butyllithium; CdCl₂*TMEDA; In tetrahydrofuran; hexane; at 0 - 20 ℃; Inert atmosphere;

With iodine; In tetrahydrofuran; hexane;
DOI:10.1039/b915274a

Reference yield:

: 14080-50-3
thieno[2,3-d]pyrimidin-4(3H)one

: 552295-08-6
4-chloro-6-iodo-thieno[2,3-d]pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: iodine; sulfuric acid; periodic acid / water / 1 h / 60 °C / Reflux

2: trichlorophosphate; N,N-dimethyl-aniline / 1 h / 105 °C / Reflux

With sulfuric acid; iodine; N,N-dimethyl-aniline; periodic acid; trichlorophosphate; In water;