Palonosetron N-Oxide

Base Information

• Chemical Name: Palonosetron N-Oxide
• CAS No.: 813425-83-1
• Molecular Formula: C₁₉H₂₄N₂O₂
• Molecular Weight: 312.412
• Hs Code.: 29339900
• Mol file: 813425-83-1.mol

Synonyms:Palonosetron N-Oxide;(3aS)-2,3,3a,4,5,6-Hexahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-1H-benz[de]isoquinolin-1-one;1H-Benz[de]isoquinolin-1-one,2,3,3a,4,5,6-hexahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-,(3aS)-

Chemical Property of Palonosetron N-Oxide

Chemical Property:

• PKA: 4.72±0.40(Predicted)
• PSA: 49.74000
• LogP: 2.56580
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Solubility.: Dichloromethane (Slightly), Methanol (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

Palonosetron N-oxide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A metabolite of Palonosetron (P165800).

Technology Process of Palonosetron N-Oxide

There total 1 articles about Palonosetron N-Oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

palonosetron (135729-60-1,135729-61-2,135729-73-6) → Palonosetron N-oxide (813425-83-1)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 25 ℃; for 1h; Solvent; Temperature; Reagent/catalyst;

upstream raw materials:

palonosetron