Carbamic acid, N-[(1S)-2-(3,4-difluorophenyl)-1-(hydroxymethyl)ethyl]-, 1,1-dimethylethyl ester

Base Information

Chemical Name:Carbamic acid, N-[(1S)-2-(3,4-difluorophenyl)-1-(hydroxymethyl)ethyl]-, 1,1-dimethylethyl ester
CAS No.:1239576-61-4
Molecular Formula:C14H19F2NO3
Molecular Weight:287.307
Hs Code.:
Mol file:1239576-61-4.mol

Synonyms:Carbamic acid, N-[(1S)-2-(3,4-difluorophenyl)-1-(hydroxymethyl)ethyl]-, 1,1-dimethylethyl ester;(S)-tert-butyl 1-(3,4-difluorophenyl)-3-hydroxypropan-2-ylcarbamate

Suppliers and Price of Carbamic acid, N-[(1S)-2-(3,4-difluorophenyl)-1-(hydroxymethyl)ethyl]-, 1,1-dimethylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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ChemScene
Carbamicacid,N-[(1S)-2-(3,4-difluorophenyl)-1-(hydroxymethyl)ethyl]-,1,1-dimethylethylester
1g
$ 1100.00

Total 2 raw suppliers

Chemical Property of Carbamic acid, N-[(1S)-2-(3,4-difluorophenyl)-1-(hydroxymethyl)ethyl]-, 1,1-dimethylethyl ester

Chemical Property:

PSA：58.56000
LogP:2.78380

Purity/Quality:

99% ^*data from raw suppliers

Carbamicacid,N-[(1S)-2-(3,4-difluorophenyl)-1-(hydroxymethyl)ethyl]-,1,1-dimethylethylester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of Carbamic acid, N-[(1S)-2-(3,4-difluorophenyl)-1-(hydroxymethyl)ethyl]-, 1,1-dimethylethyl ester

There total 2 articles about Carbamic acid, N-[(1S)-2-(3,4-difluorophenyl)-1-(hydroxymethyl)ethyl]-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1364867-97-9
(+)-2-amino-3-(3,4-difluoro)-phenyl-propan-1-ol

: 24424-99-5
di-tert-butyl dicarbonate

: 1239576-61-4
1,1-dimethylethyl [(1S)-2-(3,4-difluorophenyl)-1-(hydroxymethyl)ethyl]carbamate

Guidance literature:: In chloroform; at 0 - 20 ℃;

Reference yield: 74.0%

: 198474-90-7,1214041-87-8,205445-51-8
(S)-2-((tert-butoxycarbonyl)amino)-3-(3,4-difluorophenyl)propanoic acid

: 1239576-61-4
1,1-dimethylethyl [(1S)-2-(3,4-difluorophenyl)-1-(hydroxymethyl)ethyl]carbamate

Guidance literature:: (S)-2-((tert-butoxycarbonyl)amino)-3-(3,4-difluorophenyl)propanoic acid; With borane-THF; In tetrahydrofuran; at 0 ℃;

With acetic acid; In tetrahydrofuran; methanol;