1-Methyl-4-tosylimidazole-5-thiol

Base Information

Chemical Name:1-Methyl-4-tosylimidazole-5-thiol
CAS No.:81291-85-2
Molecular Formula:C₁₁H₁₂N₂O₂S₂
Molecular Weight:268.36
Hs Code.:
DSSTox Substance ID:DTXSID30512348
Wikidata:Q82371545
Mol file:81291-85-2.mol

Synonyms:81291-85-2;1-METHYL-4-TOSYLIMIDAZOLE-5-THIOL;1-Methyl-4-tosyl-1H-imidazole-5-thiol;3-methyl-5-(4-methylphenyl)sulfonylimidazole-4-thiol;DTXSID30512348;AKOS015964928;1-methyl-4-(4-methylbenzenesulfonyl)-1H-imidazole-5-thiol;1-Methyl-4-(4-methylbenzene-1-sulfonyl)-1H-imidazole-5-thiol

Suppliers and Price of 1-Methyl-4-tosylimidazole-5-thiol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-METHYL-4-TOSYLIMIDAZOLE-5-THIOL 95.00%
5MG
$ 499.98

Total 6 raw suppliers

Chemical Property of 1-Methyl-4-tosylimidazole-5-thiol

Chemical Property:

Vapor Pressure:1.49E-10mmHg at 25°C
Boiling Point:524.1°C at 760 mmHg
Flash Point:270.8°C
PSA：99.14000
Density:1.37g/cm³
LogP:2.93080
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:268.03401998
Heavy Atom Count:17
Complexity:358

Purity/Quality:

99% ^*data from raw suppliers

1-METHYL-4-TOSYLIMIDAZOLE-5-THIOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)C2=C(N(C=N2)C)S

Technology Process of 1-Methyl-4-tosylimidazole-5-thiol

There total 3 articles about 1-Methyl-4-tosylimidazole-5-thiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 5-(methylamino)-4-tosyl-1,3-thiazole

: 81291-85-2
1-methyl-4-tosylimidazole-5-thiol

Guidance literature:: With n-butyllithium; In tetrahydrofuran; hexane; at 20 ℃; for 0.25h;

Reference yield: 54.0%

: 38622-91-2,36635-61-7
[(p-methylphenyl)sulfonylmethyl]isonitrile

: 556-61-6
methyl thioisocyanate

: 81291-85-2
1-methyl-4-tosylimidazole-5-thiol

Guidance literature:: With n-butyllithium; In tetrahydrofuran; hexane; at -70 ℃; for 0.166667h;

Reference yield:

: 38622-91-2,36635-61-7
[(p-methylphenyl)sulfonylmethyl]isonitrile

: 81291-85-2
1-methyl-4-tosylimidazole-5-thiol

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / NaH / 1,2-dimethoxy-ethane / 1.) 0 - 5 deg C, 30 min, 2.) 30 min, r.t.

2: 89 percent / 1.6 N BuLi / tetrahydrofuran; hexane / 0.25 h / 20 °C

With n-butyllithium; sodium hydride; In tetrahydrofuran; 1,2-dimethoxyethane; hexane;