4-Amino-5-iodo-2-methylbenzonitrile

Base Information

Chemical Name:4-Amino-5-iodo-2-methylbenzonitrile
CAS No.:380241-62-3
Molecular Formula:C8H7IN2
Molecular Weight:258.061
Hs Code.:
DSSTox Substance ID:DTXSID40454381
Wikidata:Q82275876
Mol file:380241-62-3.mol

Synonyms:4-AMINO-5-IODO-2-METHYLBENZONITRILE;380241-62-3;AB3029;SCHEMBL17679946;DTXSID40454381;MFCD09909324

Suppliers and Price of 4-Amino-5-iodo-2-methylbenzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Amino-5-iodo-2-methylbenzonitrile 95+%
1g
$ 589.00

Crysdot
4-Amino-5-iodo-2-methylbenzonitrile 95+%
5g
$ 1770.00

Chemcia Scientific
4-Amino-5-iodo-2-methyl-benzonitrile 95%
5 G
$ 1395.00

American Custom Chemicals Corporation
4-AMINO-5-IODO-2-METHYLBENZONITRILE 95.00%
5MG
$ 505.70

Total 2 raw suppliers

Chemical Property of 4-Amino-5-iodo-2-methylbenzonitrile

Chemical Property:

PSA：49.81000
LogP:2.63468
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:257.96540
Heavy Atom Count:11
Complexity:184

Purity/Quality:

95% ^*data from raw suppliers

4-Amino-5-iodo-2-methylbenzonitrile 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1C#N)I)N

Technology Process of 4-Amino-5-iodo-2-methylbenzonitrile

There total 3 articles about 4-Amino-5-iodo-2-methylbenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 89001-53-6
2-cyano-5-nitrotoluene

: 380241-62-3
4-amino-5-iodo-2-methylbenzonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 12 N aq. HCl; SnCl₂*2H₂O / dioxane / 4 h

2: 4.1 g / NIS; AcOH / 3 h

With hydrogenchloride; N-iodo-succinimide; acetic acid; tin(ll) chloride; In 1,4-dioxane;
DOI:10.1021/jm010244+

Reference yield:

: 99-52-5
2-methyl-4-nitro-benzenamine

: 380241-62-3
4-amino-5-iodo-2-methylbenzonitrile

Guidance literature:: Multi-step reaction with 3 steps

1.1: aq. AcOH; H₂SO₄; NaNO₂ / 0 °C

1.2: 91 percent / aq. NaHCO₃ / benzene / 0.5 h

2.1: 12 N aq. HCl; SnCl₂*2H₂O / dioxane / 4 h

3.1: 4.1 g / NIS; AcOH / 3 h

With hydrogenchloride; N-iodo-succinimide; sulfuric acid; acetic acid; tin(ll) chloride; sodium nitrite; In 1,4-dioxane;
DOI:10.1021/jm010244+