alpha-(2-Phenylethylidene)-4-morpholineacetonitrile

Base Information

Chemical Name:alpha-(2-Phenylethylidene)-4-morpholineacetonitrile
CAS No.:33599-28-9
Molecular Formula:C₁₄H₁₆N₂O
Molecular Weight:228.294
Hs Code.:
DSSTox Substance ID:DTXSID101243606
Mol file:33599-28-9.mol

Synonyms:DTXSID101243606;33599-28-9;alpha-(2-Phenylethylidene)-4-morpholineacetonitrile

Suppliers and Price of alpha-(2-Phenylethylidene)-4-morpholineacetonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of alpha-(2-Phenylethylidene)-4-morpholineacetonitrile

Chemical Property:

Melting Point:62 °C
PSA：36.26000
LogP:1.90668
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:228.126263138
Heavy Atom Count:17
Complexity:303

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1COCCN1C(=CCC2=CC=CC=C2)C#N

Technology Process of alpha-(2-Phenylethylidene)-4-morpholineacetonitrile

There total 2 articles about alpha-(2-Phenylethylidene)-4-morpholineacetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 433216-32-1
2-morpholino-4-phenylbutanenitrile

: 33599-28-9
2-morpholin-4-yl-4-phenyl-but-2-enenitrile

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; water; at 25 ℃;
DOI:10.1246/cl.2002.122

Reference yield:

: 104-53-0
3-phenyl-propionaldehyde

: 33599-28-9
2-morpholin-4-yl-4-phenyl-but-2-enenitrile

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / 25 °C

2: mCPBA; DBU / tetrahydrofuran; H₂O / 25 °C

With 1,8-diazabicyclo[5.4.0]undec-7-ene; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; water;
DOI:10.1246/cl.2002.122