D-Ribonic acid, 2,3-anhydro-2-C-carboxy-5-deoxy-, 1,4-lactone (9CI)

Base Information

Chemical Name:D-Ribonic acid, 2,3-anhydro-2-C-carboxy-5-deoxy-, 1,4-lactone (9CI)
CAS No.:239100-64-2
Molecular Formula:C6H6O5
Molecular Weight:158.11
Hs Code.:
Mol file:239100-64-2.mol

Synonyms:D-Ribonic acid, 2,3-anhydro-2-C-carboxy-5-deoxy-, 1,4-lactone (9CI)

Suppliers and Price of D-Ribonic acid, 2,3-anhydro-2-C-carboxy-5-deoxy-, 1,4-lactone (9CI)

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of D-Ribonic acid, 2,3-anhydro-2-C-carboxy-5-deoxy-, 1,4-lactone (9CI)

Chemical Property:

PSA：76.13000
LogP:-0.84610

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of D-Ribonic acid, 2,3-anhydro-2-C-carboxy-5-deoxy-, 1,4-lactone (9CI)

There total 5 articles about D-Ribonic acid, 2,3-anhydro-2-C-carboxy-5-deoxy-, 1,4-lactone (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 239100-62-0
di-tert-butyl (R)-3-<(R)-1-(benzyloxy)ethyl>oxirane-2,2-dicarboxylate

: 239100-64-2,225509-09-1
(1S,4R,5R)-4-methyl-2-oxo-3,6-dioxabicyclo<3.1.0>hexane-1-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / H₂ / Pd(OH)2/C / methanol / 4 h / 50 °C

2: HCO₂H / 12 h / Ambient temperature

With formic acid; hydrogen; palladium dihydroxide; In methanol;
DOI:10.1016/S0040-4020(99)00367-1

Reference yield:

: 239100-59-5
di-tert-butyl 2-<(1S,2R)-2-benzyloxy-1-hydroxypropyl>malonate

: 239100-64-2,225509-09-1
(1S,4R,5R)-4-methyl-2-oxo-3,6-dioxabicyclo<3.1.0>hexane-1-carboxylic acid

Guidance literature:: Multi-step reaction with 5 steps

1: 91 percent / imidazole / dimethylformamide / 0 deg C to rt

2: LHMDS, I₂ / tetrahydrofuran / 1.5 h / -46 °C

3: 22.3 mg / TBAF / tetrahydrofuran / 1 h / -46 - -15 °C

4: 96 percent / H₂ / Pd(OH)2/C / methanol / 4 h / 50 °C

5: HCO₂H / 12 h / Ambient temperature

With 1H-imidazole; formic acid; tetrabutyl ammonium fluoride; hydrogen; iodine; lithium hexamethyldisilazane; palladium dihydroxide; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(99)00367-1

Reference yield:

: 239100-60-8
di-tert-butyl 2-<(1S,2R)-2-benzyloxy-1-<(trimethylsilyl)oxy>propyl>malonate

: 239100-64-2,225509-09-1
(1S,4R,5R)-4-methyl-2-oxo-3,6-dioxabicyclo<3.1.0>hexane-1-carboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: LHMDS, I₂ / tetrahydrofuran / 1.5 h / -46 °C

2: 22.3 mg / TBAF / tetrahydrofuran / 1 h / -46 - -15 °C

3: 96 percent / H₂ / Pd(OH)2/C / methanol / 4 h / 50 °C

4: HCO₂H / 12 h / Ambient temperature

With formic acid; tetrabutyl ammonium fluoride; hydrogen; iodine; lithium hexamethyldisilazane; palladium dihydroxide; In tetrahydrofuran; methanol;
DOI:10.1016/S0040-4020(99)00367-1