5-(Thiophen-2-yl)isoxazole-3-carbohydrazide

Base Information

Chemical Name:5-(Thiophen-2-yl)isoxazole-3-carbohydrazide
CAS No.:90004-25-4
Molecular Formula:C₈H₇N₃O₂S
Molecular Weight:209.228
Hs Code.:2934999090
European Community (EC) Number:655-244-6
Mol file:90004-25-4.mol

Synonyms:5-(thiophen-2-yl)isoxazole-3-carbohydrazide;90004-25-4;5-(thiophen-2-yl)-1,2-oxazole-3-carbohydrazide;5-(2-thienyl)-3-isoxazolecarbohydrazide;5-thiophen-2-yl-1,2-oxazole-3-carbohydrazide;5-Thiophen-2-yl-isoxazole-3-carboxylic acid hydrazide;BBL040213;MFCD05861726;STK350006;AKOS000311331;5-Thien-2-ylisoxazole-3-carbohydrazide;AS-83384;CS-0286872;EN300-230134

Suppliers and Price of 5-(Thiophen-2-yl)isoxazole-3-carbohydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5-(Thiophen-2-yl)isoxazole-3-carbohydrazide 95+%
5g
$ 615.00

Chemenu
5-(Thiophen-2-yl)isoxazole-3-carbohydrazide 95%
5g
$ 580.00

American Custom Chemicals Corporation
5-THIOPHEN-2-YL-ISOXAZOLE-3-CARBOXYLIC ACIDHYDRAZIDE 95.00%
5MG
$ 502.93

AK Scientific
5-Thiophen-2-yl-isoxazole-3-carboxylicacidhydrazide
1g
$ 658.00

Total 4 raw suppliers

Chemical Property of 5-(Thiophen-2-yl)isoxazole-3-carbohydrazide

Chemical Property:

Melting Point:143-144 °C(Solv: isopropanol (67-63-0))
PKA:10.55±0.10(Predicted)
PSA：112.88000
Density:1.416±0.06 g/cm3(Predicted)
LogP:2.28170
XLogP3:0.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:209.02589765
Heavy Atom Count:14
Complexity:227

Purity/Quality:

99% ^*data from raw suppliers

5-(Thiophen-2-yl)isoxazole-3-carbohydrazide 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CSC(=C1)C2=CC(=NO2)C(=O)NN

Technology Process of 5-(Thiophen-2-yl)isoxazole-3-carbohydrazide

There total 2 articles about 5-(Thiophen-2-yl)isoxazole-3-carbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 90924-54-2
ethyl 5-(2-thiophenyl)-isoxazole-3-carboxylate

: 90004-25-4
5-(2-Thienyl)-3-isoxazolcarbonsaeure-hydrazid

Guidance literature:: With hydrazine hydrate; In water; isopropyl alcohol;
DOI:10.1021/jo01064a050

Reference yield:

: 90923-01-6
2-hydroxyimino-4-oxo-4-thiophen-2-yl-butyric acid ethyl ester

: 90004-25-4
5-(2-Thienyl)-3-isoxazolcarbonsaeure-hydrazid

Guidance literature:: Multi-step reaction with 2 steps

1: HCl / ethanol

2: N₂H₄*H₂O / propan-2-ol; H₂O

With hydrogenchloride; hydrazine hydrate; In ethanol; water; isopropyl alcohol;
DOI:10.1021/jo01064a050