4-Benzofuranethanol

Base Information

• Chemical Name: 4-Benzofuranethanol
• CAS No.: 943906-70-5
• Molecular Formula: C10H10O2
• Molecular Weight: 162.19
• Hs Code.: 2932999099
• Mol file: 943906-70-5.mol

Synonyms:4-Benzofuranethanol

Chemical Property of 4-Benzofuranethanol

Chemical Property:

• PSA: 33.37000
• LogP: 1.91920

Purity/Quality:

4-Benzofuranethanol 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Benzofuranethanol

There total 2 articles about 4-Benzofuranethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,1-dimethylethyl benzofuran-4-yl acetate (943906-73-8) → 2-(benzo[b]furan-4-yl)ethanol (943906-70-5)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at 20 ℃; for 2h;

DOI:10.1021/jm0604528

Reference yield:

1,1-dimethylethyl 2-(6,7-dihydro-4(5H)-benzofuranylidene)acetate (943906-72-7) → 2-(benzo[b]furan-4-yl)ethanol (943906-70-5)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfur / Pd/C / 1-methyl-pyrrolidin-2-one / 4 h / 170 °C

2: 27 g / lithium aluminum hydride / diethyl ether / 2 h / 20 °C

With lithium aluminium tetrahydride; sulfur; palladium on activated charcoal; In 1-methyl-pyrrolidin-2-one; diethyl ether;

DOI:10.1021/jm0604528

Reference yield:

2-(benzo[b]furan-4-yl)ethanol (943906-70-5) + C11H21NO4S → (1R,2R)/(1S,2S)-1-(4-benzo[b]furanethoxy)-2-(4-morpholinyl)cyclohexane

Guidance literature:

2-(benzo[b]furan-4-yl)ethanol; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

C₁₁H₂₁NO₄S; In N,N-dimethyl-formamide; at 80 ℃; Further stages.;

DOI:10.1021/jm0604528

upstream raw materials:

1,1-dimethylethyl benzofuran-4-yl acetate

1,1-dimethylethyl 2-(6,7-dihydro-4(5H)-benzofuranylidene)acetate