8-ISO PROSTAGLANDIN A1

Base Information

• Chemical Name: 8-ISO PROSTAGLANDIN A1
• CAS No.: 211186-29-7
• Molecular Formula: C20H32O4
• Molecular Weight: 336.47
• Mol file: 211186-29-7.mol

Synonyms:9-OXO-15S-HYDROXY-(8BETA)-PROSTA-10,13E-DIEN-1-OIC ACID;8-ISO PROSTAGLANDIN A1

Chemical Property of 8-ISO PROSTAGLANDIN A1

Chemical Property:

• Boiling Point: 510.7±50.0 °C(Predicted)
• PKA: 4.77±0.10(Predicted)
• PSA: 74.60000
• Density: 1.086±0.06 g/cm3(Predicted)
• LogP: 4.28030

Purity/Quality:

99% ^*data from raw suppliers

8-iso Prostaglandin A1 ≥97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 8-ISO PROSTAGLANDIN A1

There total 19 articles about 8-ISO PROSTAGLANDIN A1 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

rac-(15S)-11β,15-dihydroxy-9-oxo-prost-13t-en-1-oic acid (745-65-3,7004-01-5,20348-58-7,20348-68-9,20348-69-0,20897-91-0,20897-93-2,20897-96-5,20897-98-7,21003-46-3,22468-06-0,23203-65-8,24570-01-2,25140-31-2,38360-96-2,39765-05-4,39765-17-8,39765-18-9,51064-02-9,54324-13-9,54422-21-8,55869-97-1,57759-90-7,57759-91-8,61375-94-8,63229-85-6) → (+/-)-Prostaglandin-A(1) (13641-87-7,14152-28-4,20348-61-2,20897-92-1,20897-94-3,53022-26-7,78855-68-2,211186-29-7)

Guidance literature:

DOI:10.1021/ja01014a054

Reference yield:

rac-(15R)-11β,15-dihydroxy-9-oxo-prost-13t-en-1-oic acid (745-65-3,7004-01-5,20348-58-7,20348-68-9,20348-69-0,20897-91-0,20897-93-2,20897-96-5,20897-98-7,21003-46-3,22468-06-0,23203-65-8,24570-01-2,25140-31-2,38360-96-2,39765-05-4,39765-17-8,39765-18-9,51064-02-9,54324-13-9,54422-21-8,55869-97-1,57759-90-7,57759-91-8,61375-94-8,63229-85-6) → dl-15-Epiprostaglandin A(1) (13641-87-7,14152-28-4,20348-61-2,20897-92-1,20897-94-3,53022-26-7,78855-68-2,211186-29-7)

Guidance literature:

DOI:10.1021/ja01014a054

Reference yield:

→ (+/-)-Prostaglandin-A(1) (13641-87-7,14152-28-4,20348-61-2,20897-92-1,20897-94-3,53022-26-7,78855-68-2,211186-29-7)

Guidance literature:

(+-)-11-Epiprostaglandin E(1), durch Dehydratisierung mit Saeure;

DOI:10.1021/ja01014a054

upstream raw materials:

rac-(15S)-11β,15-dihydroxy-9-oxo-prost-13t-en-1-oic acid

rac-(15R)-11β,15-dihydroxy-9-oxo-prost-13t-en-1-oic acid

1,5-dibromo-pentane

7-iodo-1-heptanol

Downstream raw materials:

Prostaglandin A⁽¹⁾-p-phenylbenzylester

7-[(1R,2S)-2-((E)-(S)-3-Hydroxy-oct-1-enyl)-5-oxo-cyclopent-3-enyl]-heptanoic acid biphenyl-4-yloxycarbonylmethyl ester

Prostaglandin A⁽¹⁾-p-bromphenacylester