1,6,8-Indolizinetriol, 7-fluorooctahydro-, 1S-(1.alpha.,6.beta.,7.beta.,8.beta.,8a.beta.)-

Base Information

Chemical Name:1,6,8-Indolizinetriol, 7-fluorooctahydro-, 1S-(1.alpha.,6.beta.,7.beta.,8.beta.,8a.beta.)-
CAS No.:156150-84-4
Molecular Formula:C₈H₁₄FNO₃
Molecular Weight:191.202
Hs Code.:
Mol file:156150-84-4.mol

Synonyms:1,6,8-Indolizinetriol, 7-fluorooctahydro-, 1S-(1.alpha.,6.beta.,7.beta.,8.beta.,8a.beta.)-

Suppliers and Price of 1,6,8-Indolizinetriol, 7-fluorooctahydro-, 1S-(1.alpha.,6.beta.,7.beta.,8.beta.,8a.beta.)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 1,6,8-Indolizinetriol, 7-fluorooctahydro-, 1S-(1.alpha.,6.beta.,7.beta.,8.beta.,8a.beta.)-

Chemical Property:

Boiling Point:367.4±42.0 °C(Predicted)
PKA:13.04±0.70(Predicted)
Density:1.45±0.1 g/cm3(Predicted)

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,6,8-Indolizinetriol, 7-fluorooctahydro-, 1S-(1.alpha.,6.beta.,7.beta.,8.beta.,8a.beta.)-

There total 3 articles about 1,6,8-Indolizinetriol, 7-fluorooctahydro-, 1S-(1.alpha.,6.beta.,7.beta.,8.beta.,8a.beta.)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 156150-94-6
Acetic acid (1S,6S,7S,8R,8aR)-1,6-diacetoxy-7-fluoro-octahydro-indolizin-8-yl ester

: 156150-84-4
7-deoxy-7-epi-7-fluorocastanospermine

Guidance literature:: With sodium methylate; In methanol;
DOI:10.1016/S0040-4039(00)76852-3

Reference yield:

: 156150-92-4
1,6,8-tri-O-acetylcastanospermine

: 156150-84-4
7-deoxy-7-epi-7-fluorocastanospermine

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / CH₂Cl₂

2: Bu₄NF / acetonitrile

3: 80 percent / NaOMe / methanol

With pyridine; tetrabutyl ammonium fluoride; sodium methylate; In methanol; dichloromethane; acetonitrile;
DOI:10.1016/S0040-4039(00)76852-3

Reference yield:

: 156150-93-5
Acetic acid (1S,6S,7R,8R,8aR)-1,6-diacetoxy-7-trifluoromethanesulfonyloxy-octahydro-indolizin-8-yl ester

: 156150-84-4
7-deoxy-7-epi-7-fluorocastanospermine

Guidance literature:: Multi-step reaction with 2 steps

1: Bu₄NF / acetonitrile

2: 80 percent / NaOMe / methanol

With tetrabutyl ammonium fluoride; sodium methylate; In methanol; acetonitrile;
DOI:10.1016/S0040-4039(00)76852-3