Cloprostenol

Base Information

Chemical Name:Cloprostenol
CAS No.:206555-98-8
Molecular Formula:C27H46O
Molecular Weight:424.922
Hs Code.:
Mol file:206555-98-8.mol

Synonyms:(5Z)-rel-7-[(1R,2R,3R,5S)-2-[(1E,3S)-4-(3-Chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoic Acid

Suppliers and Price of Cloprostenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Cloprostenol

Chemical Property:

Boiling Point:628.0±55.0 °C(Predicted)
PKA:4.76±0.10(Predicted)
PSA：107.22000
Density:1.321±0.06 g/cm3(Predicted)
LogP:3.19500
Storage Temp.:-20°C Freezer, Under Inert Atmosphere

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Aryl-oxymethyl analog of prostaglandin F2α.

Technology Process of Cloprostenol

There total 8 articles about Cloprostenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 26054-46-6
(-)-(1S,5R)-2-oxabicyclo[3.3.0]oct-6-en-3-one

: 206555-98-8
cloprostenol

Guidance literature:: Multi-step reaction with 7 steps

1: H₂SO₄

2: MeONa / methanol

3: (COCl)2, NEt₃ / dimethylsulfoxide

4: 50percent aq. NaOH, BuNEt₃Cl / CH₂Cl₂

5: (i-Bu)2Al-O-C₆H₂-(2,6-di-t-Bu,4-Me) / CH₂Cl₂ / -78 °C

6: (i-Bu)2AlH

With sodium hydroxide; oxalyl dichloride; sulfuric acid; sodium methylate; triethylbutylammonium chloride; diisobutylaluminium hydride; diisobutyl(2,6-di-tert-butyl-4- methylphenoxy)aluminum; triethylamine; In methanol; dichloromethane; dimethyl sulfoxide;

Reference yield:

: 32233-40-2
(3aR,4S,5R,6aS)-5-hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one

: 206555-98-8
cloprostenol

Guidance literature:: Multi-step reaction with 5 steps

1: (COCl)2, NEt₃ / dimethylsulfoxide

2: 50percent aq. NaOH, BuNEt₃Cl / CH₂Cl₂

3: (i-Bu)2Al-O-C₆H₂-(2,6-di-t-Bu,4-Me) / CH₂Cl₂ / -78 °C

4: (i-Bu)2AlH

With sodium hydroxide; oxalyl dichloride; triethylbutylammonium chloride; diisobutylaluminium hydride; diisobutyl(2,6-di-tert-butyl-4- methylphenoxy)aluminum; triethylamine; In dichloromethane; dimethyl sulfoxide;

Reference yield:

: 62961-72-2
Corey aldehyde

: 206555-98-8
cloprostenol

Guidance literature:: Multi-step reaction with 4 steps

1: 50percent aq. NaOH, BuNEt₃Cl / CH₂Cl₂

2: (i-Bu)2Al-O-C₆H₂-(2,6-di-t-Bu,4-Me) / CH₂Cl₂ / -78 °C

3: (i-Bu)2AlH

With sodium hydroxide; triethylbutylammonium chloride; diisobutylaluminium hydride; diisobutyl(2,6-di-tert-butyl-4- methylphenoxy)aluminum; In dichloromethane;