3-Oxocyclobutyl pivalate

Base Information

• Chemical Name: 3-Oxocyclobutyl pivalate
• CAS No.: 1071194-23-4
• Molecular Formula: C9H14O3
• Molecular Weight: 170.21
• Hs Code.: 2918300090
• Mol file: 1071194-23-4.mol

Synonyms:3-Oxocyclobutyl pivalate;2,2-Dimethylpropanoic acid 3-oxocyclobutyl ester

Chemical Property of 3-Oxocyclobutyl pivalate

Chemical Property:

• PSA: 43.37000
• LogP: 1.30720
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

3-OxocyclobutylPivalate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Oxocyclobutyl pivalate

There total 2 articles about 3-Oxocyclobutyl pivalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2,2-dichloro-3-oxocyclobutyl 2,2-dimethylpropanoate (1089709-01-2) → 3-oxocyclobutyl 2,2-dimethylpropanoate (1071194-23-4)

Guidance literature:

With acetic acid; zinc; at 0 ℃;

DOI:10.1016/j.bmcl.2012.04.060

Reference yield:

vinyl pivalate (3377-92-2,26715-88-8) → 3-oxocyclobutyl 2,2-dimethylpropanoate (1071194-23-4)

Guidance literature:

Multi-step reaction with 2 steps

1: zinc / diethyl ether / 20 °C

2: acetic acid; zinc / 0 °C

With acetic acid; zinc; In diethyl ether;

DOI:10.1016/j.bmcl.2012.04.060

Reference yield:

3-oxocyclobutyl 2,2-dimethylpropanoate (1071194-23-4) → (1s,3s)-3-(tosyloxy)cyclobutyl pivalate

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol; sodium tetrahydroborate / 1 h / 0 °C

2: pyridine / 18 h / 0 °C

With pyridine; sodium tetrahydroborate; ethanol;

upstream raw materials:

2,2-dichloro-3-oxocyclobutyl 2,2-dimethylpropanoate

vinyl pivalate