3-(NitroMethyl)-5-Methyl-4-hexenoic Acid Ethyl Ester

Base Information

• Chemical Name: 3-(NitroMethyl)-5-Methyl-4-hexenoic Acid Ethyl Ester
• CAS No.: 1136478-29-9
• Molecular Formula: C₁₀H₁₉NO₂
• Molecular Weight: 185.266
• Mol file: 1136478-29-9.mol

Synonyms:3-(NitroMethyl)-5-Methyl-4-hexenoic Acid Ethyl Ester

Chemical Property of 3-(NitroMethyl)-5-Methyl-4-hexenoic Acid Ethyl Ester

Chemical Property:

• PSA: 52.32000
• LogP: 2.18100
• Storage Temp.: Refrigerator
• Solubility.: Dichloromethane, Ethyl Acetate, Tetrahydrofuran

Purity/Quality:

98%min ^*data from raw suppliers

3-(Nitromethyl)-5-methyl-4-hexenoicAcidEthylEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3-(Nitromethyl)-5-methyl-4-hexenoic Acid Ethyl Ester is an intermediate in the preparation of rac 4,5-Dehydro Pregabalin (D230050).

Technology Process of 3-(NitroMethyl)-5-Methyl-4-hexenoic Acid Ethyl Ester

There total 1 articles about 3-(NitroMethyl)-5-Methyl-4-hexenoic Acid Ethyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C10H17NO4 (1136478-28-8) → C10H19NO2 (1136478-29-9)

Guidance literature:

C₁₀H₁₇NO₄; With ammonium formate; palladium 10% on activated carbon; In ethanol; at 70 ℃; for 36h; Heating / reflux;

With ammonia; In water; pH=7;

Reference yield:

C10H19NO2 (1136478-29-9) → 3-(aminomethyl)-5-methylhex-4-enoic acid (216576-74-8)

Guidance literature:

C₁₀H₁₉NO₂; With hydrogenchloride; water; acetic acid; for 3h; Heating / reflux;

With potassium hydroxide; In water; pH=5.5;

upstream raw materials:

C₁₀H₁₇NO₄

Downstream raw materials:

3-(aminomethyl)-5-methylhex-4-enoic acid

Refernces