(18α,19α)-16-Hydroxyurs-20-en-3-one

Base Information

• Chemical Name: (18α,19α)-16-Hydroxyurs-20-en-3-one
• CAS No.: 66394-73-8
• Molecular Formula: C30H48O2
• Molecular Weight: 440.7
• Mol file: 66394-73-8.mol

Synonyms:(18α,19α)-16-Hydroxyurs-20-en-3-one

Chemical Property of (18α,19α)-16-Hydroxyurs-20-en-3-one

Chemical Property:

• Melting Point: 190 - 193 °C (methanol)
• PSA: 37.30000
• LogP: 7.20380

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (18α,19α)-16-Hydroxyurs-20-en-3-one

There total 2 articles about (18α,19α)-16-Hydroxyurs-20-en-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

faradiol (20554-95-4) → Faradion (42482-68-8) + (16β,18α,19α)-16-hydroxyurs-20-en-3-one (66394-73-8) + (3β,18α,19α)-3-hydroxyurs-20-en-16-one

Guidance literature:

With potassium dichromate; sulfuric acid; In diethyl ether; water; at 20 ℃; for 7h;

DOI:10.1002/cbdv.201500356

Reference yield:

faradiol (20554-95-4) → (16β,18α,19α)-16-hydroxyurs-20-en-3-one (66394-73-8)

Guidance literature:

In diethyl ether; (oxidation);

Reference yield:

(16β,18α,19α)-16-hydroxyurs-20-en-3-one (66394-73-8) → 16-Oxo-ψ-taraxen (66394-76-1,66965-53-5)

Guidance literature:

Multi-step reaction with 2 steps

1: N₂H₄, KOH

2: CrO₃, aq. H₂SO₄

With chromium(VI) oxide; potassium hydroxide; sulfuric acid; hydrazine;

upstream raw materials:

faradiol

Downstream raw materials:

16β-Hydroxy-ψ-taraxen

16α-Hydroxy-ψ-taraxen

16-Oxo-ψ-taraxen

Refernces