3,4,8-trimethyl-7-(2-oxopropoxy)-2H-chromen-2-one

Base Information

Chemical Name:3,4,8-trimethyl-7-(2-oxopropoxy)-2H-chromen-2-one
CAS No.:21861-39-2
Molecular Formula:C₁₅H₁₆O₄
Molecular Weight:260.29
Hs Code.:
DSSTox Substance ID:DTXSID50359030
Nikkaji Number:J764.485J
Wikidata:Q82140013
Mol file:21861-39-2.mol

Synonyms:3,4,8-trimethyl-7-(2-oxopropoxy)-2H-chromen-2-one;21861-39-2;3,4,8-trimethyl-7-(2-oxopropoxy)chromen-2-one;CHEMBRDG-BB 6139576;DTXSID50359030;MFCD00836233;STK920992;AKOS015938823;EN300-302893

Suppliers and Price of 3,4,8-trimethyl-7-(2-oxopropoxy)-2H-chromen-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 3,4,8-trimethyl-7-(2-oxopropoxy)-2H-chromen-2-one

Chemical Property:

Vapor Pressure:3.62E-07mmHg at 25°C
Boiling Point:417.1°C at 760 mmHg
Flash Point:185.9°C
Density:1.164g/cm³
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:260.10485899
Heavy Atom Count:19
Complexity:424

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=O)OC2=C1C=CC(=C2C)OCC(=O)C)C

Technology Process of 3,4,8-trimethyl-7-(2-oxopropoxy)-2H-chromen-2-one

There total 3 articles about 3,4,8-trimethyl-7-(2-oxopropoxy)-2H-chromen-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 91963-11-0
7-hydroxy-3,4,8-trimethylcoumarin

: 78-95-5
chloroacetone

: 21861-39-2
3,4,8-Trimethyl-7-(2-oxo-propoxy)-chromen-2-one

Guidance literature:: With potassium carbonate; In acetone; for 4h; Heating;
DOI:10.1248/cpb.44.1591

Reference yield:

: 608-25-3
2-methylbenzene-1,3-diol

: 21861-39-2
3,4,8-Trimethyl-7-(2-oxo-propoxy)-chromen-2-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: sulfuric acid / 12 h / 0 °C

2.1: potassium carbonate; tetrabutylammomium bromide; potassium iodide / acetone / 0.25 h / 80 °C

2.2: 6 h / Reflux

With sulfuric acid; tetrabutylammomium bromide; potassium carbonate; potassium iodide; In acetone; 1.1: |Pechmann Condensation / 2.1: |Williamson Ether Synthesis / 2.2: |Williamson Ether Synthesis;
DOI:10.3390/molecules22101672

Reference yield:

: 609-14-3
2-acetylpropanoic acid ethyl ester

: 21861-39-2
3,4,8-Trimethyl-7-(2-oxo-propoxy)-chromen-2-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: sulfuric acid / 12 h / 0 °C

2.1: potassium carbonate; tetrabutylammomium bromide; potassium iodide / acetone / 0.25 h / 80 °C

2.2: 6 h / Reflux

With sulfuric acid; tetrabutylammomium bromide; potassium carbonate; potassium iodide; In acetone; 1.1: |Pechmann Condensation / 2.1: |Williamson Ether Synthesis / 2.2: |Williamson Ether Synthesis;
DOI:10.3390/molecules22101672