4-(2-FURANYL)-1-(4-METHOXYPHENYL)-2,3-AZETIDINEDIONE

Base Information

• Chemical Name: 4-(2-FURANYL)-1-(4-METHOXYPHENYL)-2,3-AZETIDINEDIONE
• CAS No.: 160947-56-8
• Molecular Formula: C14H11NO4
• Molecular Weight: 257.24
• Mol file: 160947-56-8.mol

Synonyms:4-(2-FURANYL)-1-(4-METHOXYPHENYL)-2,3-AZETIDINEDIONE

Chemical Property of 4-(2-FURANYL)-1-(4-METHOXYPHENYL)-2,3-AZETIDINEDIONE

Chemical Property:

• Melting Point: 89 - 91 °C
• Boiling Point: 415.4±55.0 °C(Predicted)
• PKA: -0.77±0.40(Predicted)
• PSA: 59.75000
• Density: 1.352±0.06 g/cm3(Predicted)
• LogP: 2.01020

Purity/Quality:

4-(2-FURANYL)-1-(4-METHOXYPHENYL)-2,3-AZETIDINEDIONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
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Technology Process of 4-(2-FURANYL)-1-(4-METHOXYPHENYL)-2,3-AZETIDINEDIONE

There total 11 articles about 4-(2-FURANYL)-1-(4-METHOXYPHENYL)-2,3-AZETIDINEDIONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

3-hydroxy-1-(4-methoxyphenyl)-4-(2-furyl)-2-azetidinone → 4-(furan-2-yl)-1-(4-methoxyphenyl)azetidine-2,3-dione (160947-56-8)

Guidance literature:

With phosphorus pentoxide; dimethyl sulfoxide; at 20 ℃;

Reference yield:

4-Furan-2-yl-3-hydroxy-3-(1-hydroxy-ethyl)-1-(4-methoxy-phenyl)-azetidin-2-one → 4-(furan-2-yl)-1-(4-methoxyphenyl)azetidine-2,3-dione (160947-56-8)

Guidance literature:

With sodium periodate; In methanol; water; for 48h; Yield given; Ambient temperature;

DOI:10.1021/jo00105a013

Reference yield:

4-Furan-2-yl-3-hydroxy-3-hydroxymethyl-1-(4-methoxy-phenyl)-azetidin-2-one → 4-(furan-2-yl)-1-(4-methoxyphenyl)azetidine-2,3-dione (160947-56-8)

Guidance literature:

With sodium periodate; In methanol; water; for 48h; Yield given; Ambient temperature;

DOI:10.1021/jo00105a013

upstream raw materials:

1-(p-Anisyl)-3-ethylidene-4-(2'-furyl)azetidin-2-one

1-(p-Anisyl)-4-(2'-furyl)-3-<(dimethylamino)methyl>azetidin-2-one

4-Furan-2-yl-1-(4-methoxy-phenyl)-3-methylene-azetidin-2-one

N-furfurylidene-p-anisidine

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