tert-butyl 4-(4-amino-3-isopropoxyphenyl)piperidine-1-carboxylate

Base Information

Chemical Name:tert-butyl 4-(4-amino-3-isopropoxyphenyl)piperidine-1-carboxylate
CAS No.:1445894-89-2
Molecular Formula:C₁₉H₃₀N₂O₃
Molecular Weight:334.459
Hs Code.:
Mol file:1445894-89-2.mol

Synonyms:tert-butyl 4-(4-amino-3-isopropoxyphenyl)piperidine-1-carboxylate

Suppliers and Price of tert-butyl 4-(4-amino-3-isopropoxyphenyl)piperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of tert-butyl 4-(4-amino-3-isopropoxyphenyl)piperidine-1-carboxylate

Chemical Property:

Purity/Quality:: 98%min ^*data from raw suppliers

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Technology Process of tert-butyl 4-(4-amino-3-isopropoxyphenyl)piperidine-1-carboxylate

There total 9 articles about tert-butyl 4-(4-amino-3-isopropoxyphenyl)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: C₁₉H₂₈N₂O₅

: 1445894-89-2
2-methylpropan-2-yl 4-[4-amino-3-(propan-2-yloxy)phenyl]piperidine-1-carboxylate

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In ethanol; at 20 ℃; for 16h;

Reference yield:

: 321-23-3
4-bromo-2-fluoronitrobenzene

: 1445894-89-2
2-methylpropan-2-yl 4-[4-amino-3-(propan-2-yloxy)phenyl]piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: caesium carbonate / 1.5 h / 85 °C

2: bis-triphenylphosphine-palladium(II) chloride; sodium carbonate / 1,4-dioxane; water / 1.5 h / Reflux

3: hydrogen; palladium 10% on activated carbon / methanol / 3 h / 20 °C / 7500.75 Torr

With bis-triphenylphosphine-palladium(II) chloride; palladium 10% on activated carbon; hydrogen; sodium carbonate; caesium carbonate; In 1,4-dioxane; methanol; water;