6-Chloroquinazoline-2,4-diamine

Base Information

Chemical Name:6-Chloroquinazoline-2,4-diamine
CAS No.:915402-35-6
Molecular Formula:C8H7ClN4
Molecular Weight:295.08
Hs Code.:
European Community (EC) Number:815-747-5
NSC Number:82703
DSSTox Substance ID:DTXSID70919670
Nikkaji Number:J454.368H
Wikidata:Q82892228
ChEMBL ID:CHEMBL267002
Mol file:915402-35-6.mol

Synonyms:6-chloroquinazoline-2,4-diamine;18671-95-9;6-Chloro-quinazoline-2,4-diamine;CHEMBL267002;NSC82703;915402-35-6;2,4-Quinazolinediamine, 6-chloro-;PY 359;SCHEMBL3335843;DTXSID70919670;Quinazoline,4-diamino-6-chloro-;ZMQPXDMCQOHVLV-UHFFFAOYSA-N;6-chloro-2,4-diamino-quinazoline;BDBM50404661;NSC-82703;AKOS006276353;6-Chloroquinazoline-2,4(1H,3H)-diimine;(2-amino-6-chloro-quinazolin-4-yl)-amine;EN300-1081207;Z1198161123

Suppliers and Price of 6-Chloroquinazoline-2,4-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 0 raw suppliers

Chemical Property of 6-Chloroquinazoline-2,4-diamine

Chemical Property:

PSA：79.28000
LogP:1.30780
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:194.0359239
Heavy Atom Count:13
Complexity:189

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=C1Cl)C(=NC(=N2)N)N

Technology Process of 6-Chloroquinazoline-2,4-diamine

There total 1 articles about 6-Chloroquinazoline-2,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

: 95-56-7
2-hydroxybromobenzene

: 667-27-6
Ethyl bromodifluoroacetate

: 915402-35-6
ethyl 2-(2-bromophenoxy)-2,2-difluoroacetate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 16h; Inert atmosphere;
DOI:10.1021/acs.orglett.6b03730