Δ4-Dafachronic acid

Base Information

Chemical Name:Δ4-Dafachronic acid
CAS No.:23017-97-2
Molecular Formula:C₂₇H₄₂O₃
Molecular Weight:414.629
Hs Code.:
Mol file:23017-97-2.mol

Synonyms:3-Oxocholest-4-en-26-oic acid;Δ4-Dafachronic acid;Δ4-Dafachronic Acid Exclusive

Suppliers and Price of Δ4-Dafachronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Cayman Chemical
Δ4-Dafachronic Acid ≥95%
1mg
$ 89.00

Cayman Chemical
Δ4-Dafachronic Acid ≥95%
5mg
$ 378.00

Cayman Chemical
Δ4-Dafachronic Acid ≥95%
10mg
$ 668.00

ApexBio Technology
Δ4-DafachronicAcid
5mg
$ 593.00

ApexBio Technology
Δ4-DafachronicAcid
10mg
$ 1053.00

AK Scientific
delta(4)-Dafachronicacid
10mg
$ 1001.00

AK Scientific
delta(4)-Dafachronicacid
1mg
$ 220.00

Total 6 raw suppliers

Chemical Property of Δ4-Dafachronic acid

Chemical Property:

Boiling Point:554.6±19.0 °C(Predicted)
PKA:4.81±0.21(Predicted)
PSA：54.37000
Density:1.07±0.1 g/cm3(Predicted)
LogP:6.66160

Purity/Quality:

≥95% ^*data from raw suppliers

Δ4-Dafachronic Acid ≥95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description During unfavorable environmental conditions, C. elegans larvae undergo arrest and form dauer larvae that can attach to other animals as a parasitic strategy for survival. DAF-12 is an orphan nuclear hormone receptor that regulates dauer larva diapause, reproductive development, fat metabolism, and life cycle/longevity in C. elegans. DAF-12 is required for entry into dauer when it is not bound to ligand by acting as a transcriptional repressor of target genes that favor reproductive development. Δ4-Dafachronic acid is a racemic version of a sterol-derived hormone that acts as a ligand of DAF-12. Δ4-Dafachronic acid binds to and transactivates DAF-12, rescuing hormone deficiency in transgenic dauer larvae and promoting reproductive maturation into adults. The (25S) diastereomer of Δ4-dafachronic acid is significantly more potent than its (25R) counterpart (EC50s = 23 and 66 nM, respectively).

Technology Process of Δ4-Dafachronic acid

There total 1 articles about Δ4-Dafachronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: