Purine-9-beta-D-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro)arabinoriboside

Base Information

Chemical Name:Purine-9-beta-D-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro)arabinoriboside
CAS No.:132723-01-4
Molecular Formula:C₂₄H₁₉FN₄O₅
Molecular Weight:462.437
Hs Code.:
Mol file:132723-01-4.mol

Synonyms:Purine-9-beta-D-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro)arabinoriboside;9-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-β-Darabinofuranosyl)-9H-purine;9-(3,5-Di-O-benzoyl-2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purine

Suppliers and Price of Purine-9-beta-D-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro)arabinoriboside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
((2R,3R,4S,5R)-3-(Benzoyloxy)-4-fluoro-5-(9H-purin-9-yl)tetrahydrofuran-2-yl)methylbenzoate 97%
1g
$ 1140.00

Chemenu
((2R,3R,4S,5R)-3-(benzoyloxy)-4-fluoro-5-(9H-purin-9-yl)tetrahydrofuran-2-yl)methylbenzoate 97%
1g
$ 1066.00

Alichem
((2R,3R,4S,5R)-3-(Benzoyloxy)-4-fluoro-5-(9H-purin-9-yl)tetrahydrofuran-2-yl)methylbenzoate
1g
$ 1208.40

Total 8 raw suppliers

Chemical Property of Purine-9-beta-D-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro)arabinoriboside

Chemical Property:

Boiling Point:643.9±65.0 °C(Predicted)
PKA:2.42±0.10(Predicted)
Density:1.45±0.1 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

((2R,3R,4S,5R)-3-(Benzoyloxy)-4-fluoro-5-(9H-purin-9-yl)tetrahydrofuran-2-yl)methylbenzoate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Purine-9-beta-D-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro)arabinoriboside

There total 2 articles about Purine-9-beta-D-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro)arabinoriboside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 97614-43-2
1,3,5-tri-O-benzoyl-2-deoxy-2-fluoro-α-D-arabinofuranose

: 132723-01-4
9-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-β-D-arabinofuranosyl)-9H-purine

Guidance literature:: Multi-step reaction with 2 steps

1: 30percent HBr/acetic acid

2: 1.) BSTFA / 1.) acetonitrile, RT, 30 min, 2.) a) CH₂Cl₂, b) 100 deg C, 45 min

With hydrogen bromide; N,O-Bis(trimethylsilyl)trifluoroacetamide; acetic acid;
DOI:10.1021/jm00109a018

Reference yield:

: 120-73-0,149297-77-8,51953-03-8
purine

: 97614-44-3
2-deoxy-2-fluoro-3,5-di-O-benzoyl-α-D-arabinofuranosyl bromide

: 132723-15-0
C₂₄H₁₉FN₄O₅

: 132723-01-4
9-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-β-D-arabinofuranosyl)-9H-purine

: 132723-14-9
C₂₄H₁₉FN₄O₅

Guidance literature:: With N,O-Bis(trimethylsilyl)trifluoroacetamide; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts; 1.) acetonitrile, RT, 30 min, 2.) a) CH₂Cl₂, b) 100 deg C, 45 min;
DOI:10.1021/jm00109a018