12-Phenyl-5,12-dihydroindolo[3,2-a]carbazole

Base Information

• Chemical Name: 12-Phenyl-5,12-dihydroindolo[3,2-a]carbazole
• CAS No.: 1346571-68-3
• Molecular Formula: C24H16N2
• Molecular Weight: 332.4
• Mol file: 1346571-68-3.mol

Synonyms:12-Phenyl-5,12-dihydroindolo[3,2-a]carbazole;1346571-68-3;12-phenyl-5H-indolo[3,2-c]carbazole;SCHEMBL12181359;4-(1-Adamantyl)piperazinedihydrochloride;5,12-Dihydro-12-phenyl-indolo[3,2-c]carbazole

Chemical Property of 12-Phenyl-5,12-dihydroindolo[3,2-a]carbazole

Chemical Property:

• Boiling Point: 598.8±32.0 °C(Predicted)
• PKA: 16.87±0.30(Predicted)
• PSA: 20.72000
• Density: 1.26±0.1 g/cm3(Predicted)
• LogP: 6.41820
• XLogP3: 6.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 332.131348519
• Heavy Atom Count: 26
• Complexity: 512

Purity/Quality:

98.5% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)N2C3=CC=CC=C3C4=C2C5=C(C=C4)NC6=CC=CC=C65

Technology Process of 12-Phenyl-5,12-dihydroindolo[3,2-a]carbazole

There total 6 articles about 12-Phenyl-5,12-dihydroindolo[3,2-a]carbazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

C24H16N2O2 → 12-phenyl-5,12-dihydroindole[3,2-a]carbazole (1346571-68-3)

Guidance literature:

With caesium carbonate; In dimethyl sulfoxide; at 140 - 150 ℃; Inert atmosphere;

Reference yield: 71.0%

→ 12-phenyl-5,12-dihydroindole[3,2-a]carbazole (1346571-68-3)

Guidance literature:

With triphenylphosphine; In 1,2-dichloro-benzene; for 24h; Reflux;

Reference yield:

1-bromo-9-phenyl-9H-carbazole → 12-phenyl-5,12-dihydroindole[3,2-a]carbazole (1346571-68-3)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene; water / 11 h / 70 °C / Inert atmosphere

2: caesium carbonate / dimethyl sulfoxide / 140 - 150 °C / Inert atmosphere

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; caesium carbonate; In water; dimethyl sulfoxide; toluene;

upstream raw materials:

2-nitrophenylboronic acid

2-nitrophenyl bromide

(9-phenyl-9H-carbazole-1-yl)boronic acid