5α-Androstan-11β-ol

Base Information

• Chemical Name: 5α-Androstan-11β-ol
• CAS No.: 25814-80-6
• Molecular Formula: C19H32O
• Molecular Weight: 276.46
• Mol file: 25814-80-6.mol

Synonyms:5α-Androstan-11β-ol

Chemical Property of 5α-Androstan-11β-ol

Chemical Property:

• Melting Point: 89-91 °C(Solv: ligroine (8032-32-4))
• Boiling Point: 375.9±10.0 °C(Predicted)
• PKA: 14.93±0.60(Predicted)
• PSA: 20.23000
• Density: 1.019±0.06 g/cm3(Predicted)
• LogP: 4.78010

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5α-Androstan-11β-ol

There total 16 articles about 5α-Androstan-11β-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5αH-androstan-11-one (1755-32-4) → 5α-androstan-11β-ol (25814-80-6)

Guidance literature:

With lithium aluminium tetrahydride;

DOI:10.1039/P19730000542 DOI:10.1021/jo01028a032

Reference yield:

5α-androstane-11,17-dione (1228-66-6) + 2,2'-[1,2-ethanediylbis(oxy)]bisethanol (112-27-6) → 5α-androstan-11β-ol (25814-80-6)

Guidance literature:

With potassium hydroxide; hydrazine hydrate; at 200 ℃; Behandeln des Reaktionsprodukts mit LiAlH₄ in Aether;

DOI:10.1039/jr9580004545

Reference yield:

5α-androst-2-ene-11,17-dione (565-88-8) → 5α-androstan-11β-ol (25814-80-6)

Guidance literature:

Multi-step reaction with 2 steps

1: platinum; ethyl acetate / Hydrogenation

2: N₂H₄+H₂O; KOH / 200 °C / Behandeln des Reaktionsprodukts mit LiAlH₄ in Aether

With potassium hydroxide; hydrazine hydrate; ethyl acetate; platinum;

DOI:10.1039/jr9580004545

upstream raw materials:

5α-androstane-11,17-dione

2,2'-[1,2-ethanediylbis(oxy)]bisethanol

5αH-androstan-11-one

5α-androst-2-ene-11,17-dione

Downstream raw materials:

5αH-androstan-11-one

5α-Androstan-11α-ol