7-Allyloxy-5-hydroxy-2-methylchromone

Base Information

Chemical Name:7-Allyloxy-5-hydroxy-2-methylchromone
CAS No.:16639-46-6
Molecular Formula:C13H12O4
Molecular Weight:232.23
Hs Code.:
Mol file:16639-46-6.mol

Synonyms:7-Allyloxy-5-hydroxy-2-methyl-4H-1-benzopyran-4-one;7-Allyloxy-5-hydroxy-2-methylchromone

Suppliers and Price of 7-Allyloxy-5-hydroxy-2-methylchromone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 7-Allyloxy-5-hydroxy-2-methylchromone

Chemical Property:

Melting Point:109-110 °C
Boiling Point:417.6±45.0 °C(Predicted)
PKA:6.48±0.40(Predicted)
PSA：59.67000
Density:1.251±0.06 g/cm3(Predicted)
LogP:2.37180

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 7-Allyloxy-5-hydroxy-2-methylchromone

There total 6 articles about 7-Allyloxy-5-hydroxy-2-methylchromone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 1013-69-0
eugenin

: 106-95-6
allyl bromide

: 16639-46-6
7-allyloxy-5-hydroxy-2-methyl-4H-chromen-4-one

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 3h; Inert atmosphere;
DOI:10.1021/acs.jnatprod.0c00587

Reference yield:

: 480-66-0,67471-34-5
2,4,6-trihydroxyacetophenone

: 16639-46-6
7-allyloxy-5-hydroxy-2-methyl-4H-chromen-4-one

Guidance literature:: Multi-step reaction with 4 steps

1: pyridine / 4 h / 20 °C

2: potassium carbonate / acetonitrile / 2 h / Reflux

3: water; potassium carbonate / acetonitrile; methanol / 3 h / Reflux

4: potassium carbonate / N,N-dimethyl-formamide / 3 h / 20 °C / Inert atmosphere

With pyridine; water; potassium carbonate; In methanol; N,N-dimethyl-formamide; acetonitrile; 2: |Kostanecki-Robinson Reaction / 4: |Williamson Ether Synthesis;
DOI:10.1021/acs.jnatprod.0c00587

Reference yield:

: 56147-47-8
2-methyl-4-oxo-4H-chromene-5,7-diyl diacetate

: 16639-46-6
7-allyloxy-5-hydroxy-2-methyl-4H-chromen-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: water; potassium carbonate / acetonitrile; methanol / 3 h / Reflux

2: potassium carbonate / N,N-dimethyl-formamide / 3 h / 20 °C / Inert atmosphere

With water; potassium carbonate; In methanol; N,N-dimethyl-formamide; acetonitrile; 2: |Williamson Ether Synthesis;
DOI:10.1021/acs.jnatprod.0c00587