2-[(4-Phenoxyphenyl)sulfonylmethyl]thiirane

Base Information

Chemical Name:2-[(4-Phenoxyphenyl)sulfonylmethyl]thiirane
CAS No.:292605-14-2
Deprecated CAS:329328-04-3
Molecular Formula:C15H14O3S2
Molecular Weight:306.4
Hs Code.:29349990
European Community (EC) Number:684-085-5
DSSTox Substance ID:DTXSID70432359
Nikkaji Number:J1.466.559E
Wikidata:Q27165480
Pharos Ligand ID:R76LSCFYN9MP
ChEMBL ID:CHEMBL483857
Mol file:292605-14-2.mol

Synonyms:(4-phenoxyphenylsulfonyl)methylthiirane;SB 3CT compound;SB-3CT;SB-3CT compound

Suppliers and Price of 2-[(4-Phenoxyphenyl)sulfonylmethyl]thiirane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
SB3CT
1mg
$ 50.00

TRC
SB3CT
500μg
$ 45.00

Tocris
SB3CT ≥98%(HPLC)
10
$ 314.00

Sigma-Aldrich
MMP-2/MMP-9 Inhibitor IV
500ug
$ 169.00

Sigma-Aldrich
MMP-2/MMP-9 Inhibitor IV - CAS 292605-14-2 - Calbiochem
500 μg
$ 161.87

Sigma-Aldrich
SB?3CT ≥98% (HPLC), powder
5mg
$ 296.00

Sigma-Aldrich
SB?3CT ≥98% (HPLC), powder
25mg
$ 1190.00

Medical Isotopes, Inc.
SB3CT
5 mg
$ 695.00

Medical Isotopes, Inc.
SB3CT
2.5 mg
$ 625.00

DC Chemicals
SB-3CT >98%
100 mg
$ 400.00

Total 21 raw suppliers

Chemical Property of 2-[(4-Phenoxyphenyl)sulfonylmethyl]thiirane

Chemical Property:

PSA：77.05000
LogP:4.44880
Storage Temp.:?20°C
Solubility.:DMSO: >20mg/mL
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:306.03843665
Heavy Atom Count:20
Complexity:401

Purity/Quality:

99%, ^*data from raw suppliers

SB3CT ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(S1)CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3
Uses SB 3CT is a selective and potent gelatinase inhibitor which may be used for the treatment of brain metastasis. SB?3CT has been used as irreversible inhibitor of matrix metallopeptidase 9 (MMP9) in cell cultures to exclude reciprocal regulation.

Technology Process of 2-[(4-Phenoxyphenyl)sulfonylmethyl]thiirane

There total 22 articles about 2-[(4-Phenoxyphenyl)sulfonylmethyl]thiirane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 292605-11-9
2-{[(4-phenoxyphenyl)sulfonyl]methyl}oxirane

: 292605-14-2
SB-3CT

Guidance literature:: With thiourea; In methanol; at 20 ℃;

Reference yield: 84.0%

: 868389-09-7
(S)-2-(4-phenoxyphenylsulfonylmethyl)oxirane

: 292605-14-2
(R)-2-(4-phenoxyphenylsulfonylmethyl)thiirane

Guidance literature:: With thiourea; In methanol; at 20 ℃;
DOI:10.1021/ol0517269

Reference yield: 72.0%

: 915156-04-6
4-(thiiran-2-ylmethylsulfonyl)phenol

: potassium phenyltrifluoborate

: 292605-14-2
SB-3CT

Guidance literature:: potassium phenyltrifluoborate; With dmap; copper(II) acetate monohydrate; In dichloromethane; at 20 ℃; for 0.0833333h; Inert atmosphere; Molecular sieve;

4-(thiiran-2-ylmethylsulfonyl)phenol; With oxygen; In dichloromethane; at 20 ℃; for 48h;
DOI:10.1016/j.bmcl.2010.12.076